Early dural metastasis from a case of glioblastoma with primitive neuroectodermal differentiation: A case report and literature review

Subhas K. Konar, Shyamal C. Bir, Tanmoy K. Maiti, Devi Prasad Patra, Angela C. DiPoto Brahmbhatt, Jamie A. Jacobsohn, Anil Nanda

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Glioblastoma with a primitive neuroectodermal (PNET) variant is a rare primary parenchymal tumor. Only a few cases of extraparenchymal metastasis are reported in world literature. Although the overall survival duration of glioblastoma multiforme (GBM) with primitive neuroectodermal tumor (PNET) variety may be prolonged in comparison to classical glioblastoma, the metastatic trend is completely different, and the prognosis is worse. We report an early dural metastasis of pure PNET component appearing in a case of primary glioblastoma with PNET variant. The lesson learned from this case is to look for early craniospinal metastasis in GBM patient with PNET component, even after completion of adjuvant radiochemotherapy.

Original languageEnglish (US)
Pages (from-to)78-81
Number of pages4
JournalJournal of Clinical Neuroscience
Volume35
DOIs
StatePublished - Jan 1 2017
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Surgery
  • Neurology
  • Clinical Neurology
  • Physiology (medical)

Keywords

  • Differentiation
  • Glioblastoma
  • Metastasis
  • Primary neuroectodermal tumor

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