EFFECTS OF CHRONIC ETHANOL EXPOSURE ON THE METABOLISM OF SELENIUM AND OTHER TRACE ELEMENTS.

Saud Al-Rabiai; Shamshad H. Gilani; John D. Bogden

EFFECTS OF CHRONIC ETHANOL EXPOSURE ON THE METABOLISM OF SELENIUM AND OTHER TRACE ELEMENTS.

Saud Al-Rabiai, Shamshad H. Gilani, John D. Bogden

Research output: Contribution to journal › Conference article › peer-review

Abstract

The paper reports on a study to determine if chronic ethanol administration produces changes in the metabolism of the essential elements Se, Cu, Fe, Mn and Zn using an animal model of alcoholic cardiomyopathy (AC). Eighteen male Sprague-Dawley rats were divided into three groups: an ad-lib control group (AL), a pair-fed control group (PF), and an ethanol-dosed group (ETOH). Ethanol produced substantial increases in liver Mn and decreases in liver Cu and Zn. Reduced food intake and ethanol ingestion were associated with a reduced percentage of ingested Se excreted in the urine. Deficiencies of Se, Cu, Fe, Mn and Zn in myocardial tissue are not likely to be involved in the pathogenesis of AC in the rat.

Original language	American English
Pages (from-to)	31-39
Number of pages	9
Journal	Trace Substances in Environmental Health: Proceedings of University of Missouri's Annual Conferenc
State	Published - 1984

ASJC Scopus subject areas

General Engineering

Cite this

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title = "EFFECTS OF CHRONIC ETHANOL EXPOSURE ON THE METABOLISM OF SELENIUM AND OTHER TRACE ELEMENTS.",

abstract = "The paper reports on a study to determine if chronic ethanol administration produces changes in the metabolism of the essential elements Se, Cu, Fe, Mn and Zn using an animal model of alcoholic cardiomyopathy (AC). Eighteen male Sprague-Dawley rats were divided into three groups: an ad-lib control group (AL), a pair-fed control group (PF), and an ethanol-dosed group (ETOH). Ethanol produced substantial increases in liver Mn and decreases in liver Cu and Zn. Reduced food intake and ethanol ingestion were associated with a reduced percentage of ingested Se excreted in the urine. Deficiencies of Se, Cu, Fe, Mn and Zn in myocardial tissue are not likely to be involved in the pathogenesis of AC in the rat.",

author = "Saud Al-Rabiai and Gilani, {Shamshad H.} and Bogden, {John D.}",

year = "1984",

language = "American English",

pages = "31--39",

journal = "Trace Substances in Environmental Health: Proceedings of University of Missouri's Annual Conferenc",

issn = "0361-5162",

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TY - JOUR

T1 - EFFECTS OF CHRONIC ETHANOL EXPOSURE ON THE METABOLISM OF SELENIUM AND OTHER TRACE ELEMENTS.

AU - Al-Rabiai, Saud

AU - Gilani, Shamshad H.

AU - Bogden, John D.

PY - 1984

Y1 - 1984

N2 - The paper reports on a study to determine if chronic ethanol administration produces changes in the metabolism of the essential elements Se, Cu, Fe, Mn and Zn using an animal model of alcoholic cardiomyopathy (AC). Eighteen male Sprague-Dawley rats were divided into three groups: an ad-lib control group (AL), a pair-fed control group (PF), and an ethanol-dosed group (ETOH). Ethanol produced substantial increases in liver Mn and decreases in liver Cu and Zn. Reduced food intake and ethanol ingestion were associated with a reduced percentage of ingested Se excreted in the urine. Deficiencies of Se, Cu, Fe, Mn and Zn in myocardial tissue are not likely to be involved in the pathogenesis of AC in the rat.

AB - The paper reports on a study to determine if chronic ethanol administration produces changes in the metabolism of the essential elements Se, Cu, Fe, Mn and Zn using an animal model of alcoholic cardiomyopathy (AC). Eighteen male Sprague-Dawley rats were divided into three groups: an ad-lib control group (AL), a pair-fed control group (PF), and an ethanol-dosed group (ETOH). Ethanol produced substantial increases in liver Mn and decreases in liver Cu and Zn. Reduced food intake and ethanol ingestion were associated with a reduced percentage of ingested Se excreted in the urine. Deficiencies of Se, Cu, Fe, Mn and Zn in myocardial tissue are not likely to be involved in the pathogenesis of AC in the rat.

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M3 - Conference article

SN - 0361-5162

SP - 31

EP - 39

JO - Trace Substances in Environmental Health: Proceedings of University of Missouri's Annual Conferenc

JF - Trace Substances in Environmental Health: Proceedings of University of Missouri's Annual Conferenc

ER -

EFFECTS OF CHRONIC ETHANOL EXPOSURE ON THE METABOLISM OF SELENIUM AND OTHER TRACE ELEMENTS.

Abstract

ASJC Scopus subject areas

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