TY - JOUR
T1 - Effects of ethanol sipper and social opportunity on ethanol drinking in rats
AU - Tomie, Arthur
AU - Uveges, Jillian M.
AU - Burger, Kelly M.
AU - Patterson-Buckendahl, Patricia
AU - Pohorecky, Larissa A.
N1 - Funding Information: Acknowledgements — This research was supported in part by NIAAA grant R21 AAA-12023-02 awarded to A.T., NIAAA grant R21 AA12705-01 awarded to P.P.-B. and NIAAA grant R01 AAA-10124-03 awarded to L.A.P.
PY - 2004/5
Y1 - 2004/5
N2 - Aims: The present study evaluates the effects of pairing ethanol sipper conditioned stimulus (CS) with social opportunity unconditioned stimulus (US) on CS-directed ethanol drinking in rats. Subjects were Long-Evans male rats (n = 32) deprived of neither food nor water, and the concentration of unsweetened ethanol (3 to 16%) in the sipper CS was increased across sessions. Methods: Group Paired/Ethanol (n = 12) received the ethanol sipper CS for 10 s immediately prior to 15 s of social opportunity US. Control groups received water rather than ethanol in the sipper CS (Paired/Water), or ethanol sipper CS and US presentations randomly (Random/Ethanol), or ethanol sipper CS but no social opportunity US (Sipper Only). Results: Mean ethanol intake in the Paired/Ethanol and Random/Ethanol groups exceeded 1.0 g/kg when the sipper CS contained 12%, 14% and 16% ethanol, and higher fluid intakes were observed in the Paired/Ethanol and Random/Ethanol groups than in the Paired/Water and Sipper Only groups. Conclusions: Social opportunity increased ethanol drinking, and more so than water drinking; however, autoshaping did not induce additional ethanol drinking beyond that observed in random controls.
AB - Aims: The present study evaluates the effects of pairing ethanol sipper conditioned stimulus (CS) with social opportunity unconditioned stimulus (US) on CS-directed ethanol drinking in rats. Subjects were Long-Evans male rats (n = 32) deprived of neither food nor water, and the concentration of unsweetened ethanol (3 to 16%) in the sipper CS was increased across sessions. Methods: Group Paired/Ethanol (n = 12) received the ethanol sipper CS for 10 s immediately prior to 15 s of social opportunity US. Control groups received water rather than ethanol in the sipper CS (Paired/Water), or ethanol sipper CS and US presentations randomly (Random/Ethanol), or ethanol sipper CS but no social opportunity US (Sipper Only). Results: Mean ethanol intake in the Paired/Ethanol and Random/Ethanol groups exceeded 1.0 g/kg when the sipper CS contained 12%, 14% and 16% ethanol, and higher fluid intakes were observed in the Paired/Ethanol and Random/Ethanol groups than in the Paired/Water and Sipper Only groups. Conclusions: Social opportunity increased ethanol drinking, and more so than water drinking; however, autoshaping did not induce additional ethanol drinking beyond that observed in random controls.
UR - http://www.scopus.com/inward/record.url?scp=2342650888&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=2342650888&partnerID=8YFLogxK
U2 - https://doi.org/10.1093/alcalc/agh055
DO - https://doi.org/10.1093/alcalc/agh055
M3 - Article
C2 - 15082456
VL - 39
SP - 197
EP - 202
JO - Alcohol and Alcoholism
JF - Alcohol and Alcoholism
SN - 0735-0414
IS - 3
ER -