Endoscopic Ultrasound-Guided Gallbladder Drainage Versus Percutaneous Drainage in Patients With Acute Cholecystitis Undergoing Elective Cholecystectomy

Amy Tyberg; Rodrigo Duarte-Chavez; Haroon M. Shahid; Avik Sarkar; Alexa Simon; Sardar M. Shah-Khan; Monica Gaidhane; Tayyaba F. Mohammad; John Nosher; Susannah S. Wise; Victoria Needham; Marin Kheng; Michael Lajin; Badal Sojitra; Bryan Wey; Shivangi Dorwat; Hameed Raina; Jaseem Ansari; Ashish Gandhi; Amol Bapaye; Sardar M. Shah-Khan; Matthew R. Krafft; Shyam Thakkar; Shailendra Singh; Janele R. Bane; John Y. Nasr; David P. Lee; Prashant Kedia; Martha Arevalo-Mora; Raquel S. Del Valle; Carlos Robles-Medranda; Miguel Puga-Tejada; Giuseppe Vanella; Jose Celso Ardengh; Mohammad Bilal; Dell'Anna Giuseppe; Paolo G. Arcidiacono; Michel Kahaleh

doi:10.14309/ctg.0000000000000593

Endoscopic Ultrasound-Guided Gallbladder Drainage Versus Percutaneous Drainage in Patients With Acute Cholecystitis Undergoing Elective Cholecystectomy

Amy Tyberg, Rodrigo Duarte-Chavez, Haroon M. Shahid, Avik Sarkar, Alexa Simon, Sardar M. Shah-Khan, Monica Gaidhane, Tayyaba F. Mohammad, John Nosher, Susannah S. Wise, Victoria Needham, Marin Kheng, Michael Lajin, Badal Sojitra, Bryan Wey, Shivangi Dorwat, Hameed Raina, Jaseem Ansari, Ashish Gandhi, Amol BapayeSardar M. Shah-Khan, Matthew R. Krafft, Shyam Thakkar, Shailendra Singh, Janele R. Bane, John Y. Nasr, David P. Lee, Prashant Kedia, Martha Arevalo-Mora, Raquel S. Del Valle, Carlos Robles-Medranda, Miguel Puga-Tejada, Giuseppe Vanella, Jose Celso Ardengh, Mohammad Bilal, Dell'Anna Giuseppe, Paolo G. Arcidiacono, Michel Kahaleh

Robert Wood Johnson Medical School (RWJMS), Medicine, Division of Gastroenterology

Rutgers, The State University

Research output: Contribution to journal › Article › peer-review

Abstract

INTRODUCTION: Cholecystectomy (CCY) is the gold standard treatment of acute cholecystitis (AC). Nonsurgical management of AC includes percutaneous transhepatic gallbladder drainage (PT-GBD) and endoscopic ultrasound-guided gallbladder drainage (EUS-GBD). This study aims to compare outcomes of patients who undergo CCY after having received EUS-GBD vs PT-GBD. METHODS: A multicenter international study was conducted in patients with AC who underwent EUS-GBD or PT-GBD, followed by an attempted CCY, between January 2018 and October 2021. Demographics, clinical characteristics, procedural details, postprocedure outcomes, and surgical details and outcomes were compared. RESULTS: One hundred thirty-nine patients were included: EUS-GBD in 46 patients (27% male, mean age 74 years) and PT-GBD in 93 patients (50% male, mean age 72 years). Surgical technical success was not significantly different between the 2 groups. In the EUS-GBD group, there was decreased operative time (84.2 vs 165.4 minutes, P < 0.00001), time to symptom resolution (4.2 vs 6.3 days, P = 0.005), and length of stay (5.4 vs 12.3 days, P = 0.001) compared with the PT-GBD group. There was no difference in the rate of conversion from laparoscopic to open CCY: 5 of 46 (11%) in the EUS-GBD arm and 18 of 93 (19%) in the PT-GBD group (P value 0.2324). DISCUSSION: Patients who received EUS-GBD had a significantly shorter interval between gallbladder drainage and CCY, shorter surgical procedure times, and shorter length of stay for the CCY compared with those who received PT-GBD. EUS-GBD should be considered an acceptable modality for gallbladder drainage and should not preclude patients from eventual CCY.

Original language	American English
Pages (from-to)	e00593
Journal	Clinical and Translational Gastroenterology
Volume	14
Issue number	6
DOIs	https://doi.org/10.14309/ctg.0000000000000593
State	Published - May 4 2023

ASJC Scopus subject areas

Gastroenterology

Keywords

EUS gall bladder drainage
EUS-GBD
cholecystectomy
cholecystitis
percutaneous

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10.14309/ctg.0000000000000593

Cite this

Tyberg, A., Duarte-Chavez, R., Shahid, H. M., Sarkar, A., Simon, A., Shah-Khan, S. M., Gaidhane, M., Mohammad, T. F., Nosher, J., Wise, S. S., Needham, V., Kheng, M., Lajin, M., Sojitra, B., Wey, B., Dorwat, S., Raina, H., Ansari, J., Gandhi, A., ... Kahaleh, M. (2023). Endoscopic Ultrasound-Guided Gallbladder Drainage Versus Percutaneous Drainage in Patients With Acute Cholecystitis Undergoing Elective Cholecystectomy. Clinical and Translational Gastroenterology, 14(6), e00593. https://doi.org/10.14309/ctg.0000000000000593

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title = "Endoscopic Ultrasound-Guided Gallbladder Drainage Versus Percutaneous Drainage in Patients With Acute Cholecystitis Undergoing Elective Cholecystectomy",

abstract = "INTRODUCTION: Cholecystectomy (CCY) is the gold standard treatment of acute cholecystitis (AC). Nonsurgical management of AC includes percutaneous transhepatic gallbladder drainage (PT-GBD) and endoscopic ultrasound-guided gallbladder drainage (EUS-GBD). This study aims to compare outcomes of patients who undergo CCY after having received EUS-GBD vs PT-GBD. METHODS: A multicenter international study was conducted in patients with AC who underwent EUS-GBD or PT-GBD, followed by an attempted CCY, between January 2018 and October 2021. Demographics, clinical characteristics, procedural details, postprocedure outcomes, and surgical details and outcomes were compared. RESULTS: One hundred thirty-nine patients were included: EUS-GBD in 46 patients (27% male, mean age 74 years) and PT-GBD in 93 patients (50% male, mean age 72 years). Surgical technical success was not significantly different between the 2 groups. In the EUS-GBD group, there was decreased operative time (84.2 vs 165.4 minutes, P < 0.00001), time to symptom resolution (4.2 vs 6.3 days, P = 0.005), and length of stay (5.4 vs 12.3 days, P = 0.001) compared with the PT-GBD group. There was no difference in the rate of conversion from laparoscopic to open CCY: 5 of 46 (11%) in the EUS-GBD arm and 18 of 93 (19%) in the PT-GBD group (P value 0.2324). DISCUSSION: Patients who received EUS-GBD had a significantly shorter interval between gallbladder drainage and CCY, shorter surgical procedure times, and shorter length of stay for the CCY compared with those who received PT-GBD. EUS-GBD should be considered an acceptable modality for gallbladder drainage and should not preclude patients from eventual CCY.",

keywords = "EUS gall bladder drainage, EUS-GBD, cholecystectomy, cholecystitis, percutaneous",

author = "Amy Tyberg and Rodrigo Duarte-Chavez and Shahid, {Haroon M.} and Avik Sarkar and Alexa Simon and Shah-Khan, {Sardar M.} and Monica Gaidhane and Mohammad, {Tayyaba F.} and John Nosher and Wise, {Susannah S.} and Victoria Needham and Marin Kheng and Michael Lajin and Badal Sojitra and Bryan Wey and Shivangi Dorwat and Hameed Raina and Jaseem Ansari and Ashish Gandhi and Amol Bapaye and Shah-Khan, {Sardar M.} and Krafft, {Matthew R.} and Shyam Thakkar and Shailendra Singh and Bane, {Janele R.} and Nasr, {John Y.} and Lee, {David P.} and Prashant Kedia and Martha Arevalo-Mora and {Del Valle}, {Raquel S.} and Carlos Robles-Medranda and Miguel Puga-Tejada and Giuseppe Vanella and Ardengh, {Jose Celso} and Mohammad Bilal and Dell'Anna Giuseppe and Arcidiacono, {Paolo G.} and Michel Kahaleh",

note = "Publisher Copyright: {\textcopyright} 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.",

year = "2023",

month = may,

day = "4",

doi = "10.14309/ctg.0000000000000593",

language = "American English",

volume = "14",

pages = "e00593",

journal = "Clinical and Translational Gastroenterology",

issn = "2155-384X",

publisher = "Nature Publishing Group",

number = "6",

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Tyberg, A, Duarte-Chavez, R, Shahid, HM, Sarkar, A, Simon, A, Shah-Khan, SM, Gaidhane, M, Mohammad, TF, Nosher, J, Wise, SS, Needham, V, Kheng, M, Lajin, M, Sojitra, B, Wey, B, Dorwat, S, Raina, H, Ansari, J, Gandhi, A, Bapaye, A, Shah-Khan, SM, Krafft, MR, Thakkar, S, Singh, S, Bane, JR, Nasr, JY, Lee, DP, Kedia, P, Arevalo-Mora, M, Del Valle, RS, Robles-Medranda, C, Puga-Tejada, M, Vanella, G, Ardengh, JC, Bilal, M, Giuseppe, DA, Arcidiacono, PG & Kahaleh, M 2023, 'Endoscopic Ultrasound-Guided Gallbladder Drainage Versus Percutaneous Drainage in Patients With Acute Cholecystitis Undergoing Elective Cholecystectomy', Clinical and Translational Gastroenterology, vol. 14, no. 6, pp. e00593. https://doi.org/10.14309/ctg.0000000000000593

Endoscopic Ultrasound-Guided Gallbladder Drainage Versus Percutaneous Drainage in Patients With Acute Cholecystitis Undergoing Elective Cholecystectomy. / Tyberg, Amy; Duarte-Chavez, Rodrigo; Shahid, Haroon M. et al.
In: Clinical and Translational Gastroenterology, Vol. 14, No. 6, 04.05.2023, p. e00593.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Endoscopic Ultrasound-Guided Gallbladder Drainage Versus Percutaneous Drainage in Patients With Acute Cholecystitis Undergoing Elective Cholecystectomy

AU - Tyberg, Amy

AU - Duarte-Chavez, Rodrigo

AU - Shahid, Haroon M.

AU - Sarkar, Avik

AU - Simon, Alexa

AU - Shah-Khan, Sardar M.

AU - Gaidhane, Monica

AU - Mohammad, Tayyaba F.

AU - Nosher, John

AU - Wise, Susannah S.

AU - Needham, Victoria

AU - Kheng, Marin

AU - Lajin, Michael

AU - Sojitra, Badal

AU - Wey, Bryan

AU - Dorwat, Shivangi

AU - Raina, Hameed

AU - Ansari, Jaseem

AU - Gandhi, Ashish

AU - Bapaye, Amol

AU - Shah-Khan, Sardar M.

AU - Krafft, Matthew R.

AU - Thakkar, Shyam

AU - Singh, Shailendra

AU - Bane, Janele R.

AU - Nasr, John Y.

AU - Lee, David P.

AU - Kedia, Prashant

AU - Arevalo-Mora, Martha

AU - Del Valle, Raquel S.

AU - Robles-Medranda, Carlos

AU - Puga-Tejada, Miguel

AU - Vanella, Giuseppe

AU - Ardengh, Jose Celso

AU - Bilal, Mohammad

AU - Giuseppe, Dell'Anna

AU - Arcidiacono, Paolo G.

AU - Kahaleh, Michel

PY - 2023/5/4

Y1 - 2023/5/4

N2 - INTRODUCTION: Cholecystectomy (CCY) is the gold standard treatment of acute cholecystitis (AC). Nonsurgical management of AC includes percutaneous transhepatic gallbladder drainage (PT-GBD) and endoscopic ultrasound-guided gallbladder drainage (EUS-GBD). This study aims to compare outcomes of patients who undergo CCY after having received EUS-GBD vs PT-GBD. METHODS: A multicenter international study was conducted in patients with AC who underwent EUS-GBD or PT-GBD, followed by an attempted CCY, between January 2018 and October 2021. Demographics, clinical characteristics, procedural details, postprocedure outcomes, and surgical details and outcomes were compared. RESULTS: One hundred thirty-nine patients were included: EUS-GBD in 46 patients (27% male, mean age 74 years) and PT-GBD in 93 patients (50% male, mean age 72 years). Surgical technical success was not significantly different between the 2 groups. In the EUS-GBD group, there was decreased operative time (84.2 vs 165.4 minutes, P < 0.00001), time to symptom resolution (4.2 vs 6.3 days, P = 0.005), and length of stay (5.4 vs 12.3 days, P = 0.001) compared with the PT-GBD group. There was no difference in the rate of conversion from laparoscopic to open CCY: 5 of 46 (11%) in the EUS-GBD arm and 18 of 93 (19%) in the PT-GBD group (P value 0.2324). DISCUSSION: Patients who received EUS-GBD had a significantly shorter interval between gallbladder drainage and CCY, shorter surgical procedure times, and shorter length of stay for the CCY compared with those who received PT-GBD. EUS-GBD should be considered an acceptable modality for gallbladder drainage and should not preclude patients from eventual CCY.

AB - INTRODUCTION: Cholecystectomy (CCY) is the gold standard treatment of acute cholecystitis (AC). Nonsurgical management of AC includes percutaneous transhepatic gallbladder drainage (PT-GBD) and endoscopic ultrasound-guided gallbladder drainage (EUS-GBD). This study aims to compare outcomes of patients who undergo CCY after having received EUS-GBD vs PT-GBD. METHODS: A multicenter international study was conducted in patients with AC who underwent EUS-GBD or PT-GBD, followed by an attempted CCY, between January 2018 and October 2021. Demographics, clinical characteristics, procedural details, postprocedure outcomes, and surgical details and outcomes were compared. RESULTS: One hundred thirty-nine patients were included: EUS-GBD in 46 patients (27% male, mean age 74 years) and PT-GBD in 93 patients (50% male, mean age 72 years). Surgical technical success was not significantly different between the 2 groups. In the EUS-GBD group, there was decreased operative time (84.2 vs 165.4 minutes, P < 0.00001), time to symptom resolution (4.2 vs 6.3 days, P = 0.005), and length of stay (5.4 vs 12.3 days, P = 0.001) compared with the PT-GBD group. There was no difference in the rate of conversion from laparoscopic to open CCY: 5 of 46 (11%) in the EUS-GBD arm and 18 of 93 (19%) in the PT-GBD group (P value 0.2324). DISCUSSION: Patients who received EUS-GBD had a significantly shorter interval between gallbladder drainage and CCY, shorter surgical procedure times, and shorter length of stay for the CCY compared with those who received PT-GBD. EUS-GBD should be considered an acceptable modality for gallbladder drainage and should not preclude patients from eventual CCY.

KW - EUS gall bladder drainage

KW - EUS-GBD

KW - cholecystectomy

KW - cholecystitis

KW - percutaneous

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UR - http://www.scopus.com/inward/citedby.url?scp=85164209149&partnerID=8YFLogxK

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DO - 10.14309/ctg.0000000000000593

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SN - 2155-384X

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SP - e00593

JO - Clinical and Translational Gastroenterology

JF - Clinical and Translational Gastroenterology

IS - 6

ER -

Endoscopic Ultrasound-Guided Gallbladder Drainage Versus Percutaneous Drainage in Patients With Acute Cholecystitis Undergoing Elective Cholecystectomy

Abstract

ASJC Scopus subject areas

Keywords

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