Feed Intake, Body Weight, Body Condition Score, Musculation, and Immunocompetence in Aged Mares Given Equine Somatotropin

K. Malinowski, R. A. Christensen, A. Konopka, C. G. Scanes, H. D. Hafs

Research output: Contribution to journalArticle

42 Scopus citations

Abstract

Sixteen 20- to 26-yr-old mares were given 0, 6.25, or 12.5 mg/d equine somatotropin (eST) to determine whether aged mares respond to ST with changes in feed intake, body weight, body condition score (based mostly on fat cover), or immunocompetence. Neither dry matter intake, body weight, nor body condition scores were altered during the 6 wk of eST injection. However, based on photographs taken to evaluate musculation before and after treatment (scores 0 to 4), mares given eST developed greater (P < .07) muscle definition (1.8 ± .6 and 2.5 ± .6 for 6.25 and 12.5 mg eST/d, respectively) than control mares (.7 ± .4). Total circulating leukocytes increased (P < .05) in both of the eST-treated groups during the 6-wk injection period, caused by an increase (P < .05) in granulocytes. Lymphocyte numbers were not altered. Granulocyte oxidative burst activity was not altered by eST treatment. Although lymphocyte proliferative responses to phytohemagglutinin, pokeweed mitogen, or lipopolysaccharide were not altered during the treatment period, lymphocyte proliferation in response to phytohemagglutinin and pokeweed mitogen increased twofold in eST-treated horses at 2 wk after eST treatment. In overview, the increased musculation and the increase in granulocyte numbers in mares given eST suggest that eST supplementation may improve the health and well-being of aged mares.

Original languageEnglish (US)
Pages (from-to)755-760
Number of pages6
JournalJournal of animal science
Volume75
Issue number3
DOIs
StatePublished - Mar 1997

All Science Journal Classification (ASJC) codes

  • Food Science
  • Genetics
  • Animal Science and Zoology

Keywords

  • Horses
  • Immunocompetence
  • Leukocytes
  • Somatotropin

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