From sexual behavior to analgesia to an antinociceptive agent: Glycinamide

Porfirio Gómora-Arrati, Y. Galicia-Aguas, Oscar González-Flores, Barry R. Komisaruk

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Previous research in our laboratory showed that stimulation of the vagina in rats with a probe inhibits withdrawal responses to noxious stimulation (Komisaruk and Larsson, 1971) and inhibits thalamic sensory neuronal response to noxious, but not innocuous, stimulation, providing evidence that vaginal stimulation induces analgesia (Komisaruk and Wallman, 1977). Subsequently, we reported that natural mating behavior in female rats produces analgesia during intromissions, and especially ejaculation, that is more potent than a supra-analgesic dose of morphine (Gomora, Beyer, Gonzalez-Mariscal, and Komisaruk, 1994).

Original languageEnglish (US)
Title of host publicationBehavioral Neuroendocrinology
PublisherCRC Press
Pages279-285
Number of pages7
ISBN (Electronic)9781315388052
ISBN (Print)9781498731911
DOIs
StatePublished - Jan 1 2017

ASJC Scopus subject areas

  • Neuroscience(all)
  • Medicine(all)

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