Abstract
TGFβ-like ligands are involved in many different developmental processes that pattern a variety of tissues in invertebrates and vertebrates. In the last few years, rapid progress has been made toward elucidating the developmental roles of the TGFβ-like pathways and identifying the novel components involved in transducing their signals, particularly the newly discovered Smads. This rapid progress has been the result of a synergy between classical genetic approaches and biochemical approaches, and this combined approach is likely to propel future understanding of the signaling pathway use by TGFβ.
| Original language | American English |
|---|---|
| Pages (from-to) | 1-9 |
| Number of pages | 9 |
| Journal | Cytokine and Growth Factor Reviews |
| Volume | 8 |
| Issue number | 1 |
| DOIs | |
| State | Published - Mar 1997 |
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Immunology and Allergy
- Immunology
- General Biochemistry, Genetics and Molecular Biology
Keywords
- Caenorhabditis elegans
- Drosophila
- Signal transduction
- Smad proteins
- TGFβ