Abstract
Gestational trophoblastic disease (GTD) ranges from premaLignant hydatidiform mole through maLignant invasive mole and choriocarcinoma, as well as more rare lesions of intermediate trophoblastic origin. The most common form of GTD, hydatidiform mole, represents aberrant development of a pregnancy due to specific genetic alterations and is the greatest predisposing risk factor for the development of persistent GTD. While pathologists classify the entities predominantly by histology, the cLinical management of persistent GTD is more often dictated by parameters such as the serum β-hCG level.
| Original language | American English |
|---|---|
| Title of host publication | Pathobiology of Human Disease |
| Subtitle of host publication | A Dynamic Encyclopedia of Disease Mechanisms |
| Publisher | Elsevier Inc. |
| Pages | 2443-2455 |
| Number of pages | 13 |
| ISBN (Electronic) | 9780123864567 |
| ISBN (Print) | 9780123864574 |
| DOIs | |
| State | Published - Jan 1 2014 |
ASJC Scopus subject areas
- General Medicine
Keywords
- Beta-subunit
- Biological
- Choriocarcinoma
- Chorionic gonadotropin
- EpitheLioid trophoblastic tumor
- Exaggerated placental site
- Gestational trophoblastic disease
- Gestational trophoblastic neoplasia
- Human
- Hydatidiform mole
- Invasive mole
- Molecular diagnostics
- Placental site nodule
- Placental site plaque
- Placental site trophoblastic tumor
- Pregnancy
- Trophoblastic neoplasms
- Tumor markers
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