Green fluorescent protein as a marker for gene expression

Martin Chalfie, Yuan Tu, Ghia Euskirchen, William W. Ward, Douglas C. Prasher

Research output: Contribution to journalArticlepeer-review

5247 Scopus citations


A complementary DNA for the Aequorea victoria green fluorescent protein (GFP) produces a fluorescent product when expressed in prokaryotic (Escherichia coli) or eukaryotic (Caenorhabditis elegans) cells. Because exogenous substrates and cofactors are not required for this fluorescence, GFP expression can be used to monitor gene expression and protein localization in living organisms.

Original languageEnglish (US)
Pages (from-to)802-805
Number of pages4
Issue number5148
StatePublished - 1994

ASJC Scopus subject areas

  • General


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