HLA-A2-Restricted CD8+-Cytotoxic-T-Cell Responses to Novel Epitopes in Mycobacterium tuberculosis Superoxide Dismutase, Alanine Dehydrogenase, and Glutamine Synthetase

Yuzhi Dong, Sandra Demaria, Xuming Sun, Fabio R. Santori, Bill M. Jesdale, Anne S. De Groot, William N. Rom, Yuri Bushkin

Research output: Contribution to journalArticlepeer-review

41 Scopus citations

Abstract

Major histocompatibility complex class I-restricted CD8+ cytotoxic T lymphocytes (CTL) are implicated in protective Th1 immunity to Mycobacterium tuberculosis infection. We report the identification of three novel HLA-A*0201-restricted CTL epitopes within mycobacterial superoxide dismutase (SodA), L-alanine dehydrogenase (AlaDH), and L-glutamine synthetase (GlnS) proteins.

Original languageEnglish (US)
Pages (from-to)2412-2415
Number of pages4
JournalInfection and immunity
Volume72
Issue number4
DOIs
StatePublished - Apr 2004
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Infectious Diseases
  • Parasitology
  • Microbiology
  • Immunology

Fingerprint

Dive into the research topics of 'HLA-A2-Restricted CD8<sup>+</sup>-Cytotoxic-T-Cell Responses to Novel Epitopes in Mycobacterium tuberculosis Superoxide Dismutase, Alanine Dehydrogenase, and Glutamine Synthetase'. Together they form a unique fingerprint.

Cite this