Improved performance of deterministic lateral displacement arrays with triangular posts

Kevin Loutherback, Kevin S. Chou, Jonathan Newman, Jason Puchalla, Robert Hamilton Austin, James Christopher Sturm

Research output: Contribution to journalArticle

88 Citations (Scopus)

Abstract

Deterministic lateral displacement arrays have shown great promise for size-based particle analysis and purification in medicine and biology. Here, we demonstrate that the use of an array of triangular rather than circular posts significantly enhances the performance of these devices by reducing clogging, lowering hydrostatic pressure requirements, and increasing the range of displacement characteristics. Experimental data and theoretical models are presented to create a compelling argument that future designs of deterministic lateral displacement arrays should employ triangular posts. The effect of practical considerations, such as vertex rounding, post size, and shape, is also discussed.

Original languageEnglish (US)
Pages (from-to)1143-1149
Number of pages7
JournalMicrofluidics and Nanofluidics
Volume9
Issue number6
DOIs
StatePublished - Dec 1 2010

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Hydrostatic pressure
Medicine
Purification
plugging
biology
medicine
purification
hydrostatic pressure
apexes
requirements

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Materials Chemistry

Cite this

Loutherback, Kevin ; Chou, Kevin S. ; Newman, Jonathan ; Puchalla, Jason ; Austin, Robert Hamilton ; Sturm, James Christopher. / Improved performance of deterministic lateral displacement arrays with triangular posts. In: Microfluidics and Nanofluidics. 2010 ; Vol. 9, No. 6. pp. 1143-1149.
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Improved performance of deterministic lateral displacement arrays with triangular posts. / Loutherback, Kevin; Chou, Kevin S.; Newman, Jonathan; Puchalla, Jason; Austin, Robert Hamilton; Sturm, James Christopher.

In: Microfluidics and Nanofluidics, Vol. 9, No. 6, 01.12.2010, p. 1143-1149.

Research output: Contribution to journalArticle

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