Abstract
To our knowledge, this is the first demonstration of in vivo depth-resolved birefringence measurements of the human retinal nerve fiber layer (RNFL) by use of polarization-sensitive optical coherence tomography (PS-OCT). Because glaucoma causes nerve fiber layer damage, which may cause loss of retinal birefringence, PS-OCT is a potentially useful technique for the early detection of glaucoma. We built a fiber-based PS-OCT setup that produces quasi-real-time images of the human retina in vivo. Preliminary measurements of a healthy volunteer showed that the double-pass phase retardation per unit depth of the RNFL near the optic nerve head is 39 ± 6°/100 μm.
| Original language | American English |
|---|---|
| Pages (from-to) | 1610-1612 |
| Number of pages | 3 |
| Journal | Optics Letters |
| Volume | 27 |
| Issue number | 18 |
| DOIs | |
| State | Published - Sep 15 2002 |
| Externally published | Yes |
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics