Increasing secondary metabolite production in plant-cell culture by redirecting transport

Peter Brodelius, Henrik Pedersen

Research output: Contribution to journalReview articlepeer-review

46 Scopus citations

Abstract

Various approaches for redirecting transport of secondary metabolites in plant-cell suspension cultures have been attempted in an effort to increase productivity. Little is understood of the transport mechanisms or their regulation, and many of the extractive methods which involve membrane permeabilization have an adverse effect on cell viability. Increasing the activity of metabolic pathways by elicitation, in conjunction with end-product removal and accumulation in an extractive phase, has proven to be the most successful strategy so far.

Original languageEnglish (US)
Pages (from-to)30-36
Number of pages7
JournalTrends in Biotechnology
Volume11
Issue number1
DOIs
StatePublished - Jan 1993

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering

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