TY - JOUR
T1 - Insecticide solvents
T2 - Interference with insecticidal action
AU - Brattsten, L. B.
AU - Wilkinson, C. F.
PY - 1977
Y1 - 1977
N2 - Several commercial solvent mixtures commonly used as insecticide carriers in spray formulations increase by more than threefold the microsomal N-demethylation of p-chloro N-methylaniline in midgut preparations of southern army-worm (Spodoptera eridania) larvae exposed orally to the test solvents. Under laboratory conditions, the same solvent mixtures exhibit a protective action against the in vivo toxicity of the insecticide carbaryl to the larvae. The data are discussed with respect to possible solvent-insecticide interactions occurring under field conditions and, more broadly, to potential toxicological hazards of these solvents to humans.
AB - Several commercial solvent mixtures commonly used as insecticide carriers in spray formulations increase by more than threefold the microsomal N-demethylation of p-chloro N-methylaniline in midgut preparations of southern army-worm (Spodoptera eridania) larvae exposed orally to the test solvents. Under laboratory conditions, the same solvent mixtures exhibit a protective action against the in vivo toxicity of the insecticide carbaryl to the larvae. The data are discussed with respect to possible solvent-insecticide interactions occurring under field conditions and, more broadly, to potential toxicological hazards of these solvents to humans.
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U2 - https://doi.org/10.1126/science.860135
DO - https://doi.org/10.1126/science.860135
M3 - Article
C2 - 860135
SN - 0036-8075
VL - 196
SP - 1211
EP - 1213
JO - Science (New York, N.Y.)
JF - Science (New York, N.Y.)
IS - 4295
ER -