Interrogating Metabolism in Brain Cancer

Travis C. Salzillo, Jingzhe Hu, Linda Nguyen, Nicholas Whiting, Jaehyuk Lee, Joseph Weygand, Prasanta Dutta, Shivanand Pudakalakatti, Niki Zacharias Millward, Seth T. Gammon, Frederick F. Lang, Amy B. Heimberger, Pratip K. Bhattacharya

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

This article reviews existing and emerging techniques of interrogating metabolism in brain cancer from well-established proton magnetic resonance spectroscopy to the promising hyperpolarized metabolic imaging and chemical exchange saturation transfer and emerging techniques of imaging inflammation. Some of these techniques are at an early stage of development and clinical trials are in progress in patients to establish the clinical efficacy. It is likely that in vivo metabolomics and metabolic imaging is the next frontier in brain cancer diagnosis and assessing therapeutic efficacy; with the combined knowledge of genomics and proteomics a complete understanding of tumorigenesis in brain might be achieved.

Original languageEnglish (US)
Pages (from-to)687-703
Number of pages17
JournalMagnetic Resonance Imaging Clinics of North America
Volume24
Issue number4
DOIs
StatePublished - Nov 1 2016
Externally publishedYes

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Brain Neoplasms
Metabolomics
Genomics
Proteomics
Carcinogenesis
Clinical Trials
Inflammation
Brain
Therapeutics
Proton Magnetic Resonance Spectroscopy

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Salzillo, T. C., Hu, J., Nguyen, L., Whiting, N., Lee, J., Weygand, J., ... Bhattacharya, P. K. (2016). Interrogating Metabolism in Brain Cancer. Magnetic Resonance Imaging Clinics of North America, 24(4), 687-703. https://doi.org/10.1016/j.mric.2016.07.003
Salzillo, Travis C. ; Hu, Jingzhe ; Nguyen, Linda ; Whiting, Nicholas ; Lee, Jaehyuk ; Weygand, Joseph ; Dutta, Prasanta ; Pudakalakatti, Shivanand ; Millward, Niki Zacharias ; Gammon, Seth T. ; Lang, Frederick F. ; Heimberger, Amy B. ; Bhattacharya, Pratip K. / Interrogating Metabolism in Brain Cancer. In: Magnetic Resonance Imaging Clinics of North America. 2016 ; Vol. 24, No. 4. pp. 687-703.
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author = "Salzillo, {Travis C.} and Jingzhe Hu and Linda Nguyen and Nicholas Whiting and Jaehyuk Lee and Joseph Weygand and Prasanta Dutta and Shivanand Pudakalakatti and Millward, {Niki Zacharias} and Gammon, {Seth T.} and Lang, {Frederick F.} and Heimberger, {Amy B.} and Bhattacharya, {Pratip K.}",
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Salzillo, TC, Hu, J, Nguyen, L, Whiting, N, Lee, J, Weygand, J, Dutta, P, Pudakalakatti, S, Millward, NZ, Gammon, ST, Lang, FF, Heimberger, AB & Bhattacharya, PK 2016, 'Interrogating Metabolism in Brain Cancer', Magnetic Resonance Imaging Clinics of North America, vol. 24, no. 4, pp. 687-703. https://doi.org/10.1016/j.mric.2016.07.003

Interrogating Metabolism in Brain Cancer. / Salzillo, Travis C.; Hu, Jingzhe; Nguyen, Linda; Whiting, Nicholas; Lee, Jaehyuk; Weygand, Joseph; Dutta, Prasanta; Pudakalakatti, Shivanand; Millward, Niki Zacharias; Gammon, Seth T.; Lang, Frederick F.; Heimberger, Amy B.; Bhattacharya, Pratip K.

In: Magnetic Resonance Imaging Clinics of North America, Vol. 24, No. 4, 01.11.2016, p. 687-703.

Research output: Contribution to journalReview article

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T1 - Interrogating Metabolism in Brain Cancer

AU - Salzillo, Travis C.

AU - Hu, Jingzhe

AU - Nguyen, Linda

AU - Whiting, Nicholas

AU - Lee, Jaehyuk

AU - Weygand, Joseph

AU - Dutta, Prasanta

AU - Pudakalakatti, Shivanand

AU - Millward, Niki Zacharias

AU - Gammon, Seth T.

AU - Lang, Frederick F.

AU - Heimberger, Amy B.

AU - Bhattacharya, Pratip K.

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