Intraoperative functional MRI using a real-time neurosurgical navigation system

Joseph A. Maldjian, Michael Schulder, Wen Ching Liu, In Ki Mun, David Hirschorn, Raj Murthy, Peter Carmel, Andrew Kalnin

Research output: Contribution to journalArticlepeer-review

68 Scopus citations


A 42-year-old-man had focal left hand motor seizures. MR studies demonstrated a right posterior frontal brain tumor. Functional MRI was performed, localizing the motor cortex posterior to the lesion. The functional images were integrated with a neurosurgical navigation computer. A real-time intraoperative display of the anatomic and functional images was produced, registered to a neurosurgical probe. Excellent correlation was demonstrated between the functional maps and invasive electrophysiologic mapping performed at the time of craniotomy.

Original languageEnglish (US)
Pages (from-to)910-912
Number of pages3
JournalJournal of Computer Assisted Tomography
Issue number6
StatePublished - 1997

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


  • Brain, diseases
  • Brain, seizures
  • Magnetic resonance imaging, functional


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