Intraperitoneal chemotherapy in a pregnant woman with ovarian cancer

Esther R. Smith; Mark E. Borowsky; Vanita Dharan Jain

doi:10.1097/AOG.0b013e31828a845a

Intraperitoneal chemotherapy in a pregnant woman with ovarian cancer

Esther R. Smith, Mark E. Borowsky, Vanita Dharan Jain

School of Medicine

Hackensack Meridian School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Background: Ovarian cancer diagnosed in pregnancy is rare. There is limited evidence to guide the choice of optimal chemotherapeutic management for treatment of disease during pregnancy. Case: A 36-year-old primigravid woman was diagnosed with stage IIB grade III serous adenocarcinoma at 12 weeks of gestation. After extensive counseling, she opted for intraperitoneal chemotherapy. She received four cycles during the course of the pregnancy, and treatment was complicated by thrombocytopenia and mild preeclampsia. Delivery occurred by cesarean at 37 weeks of gestation, resulting in the birth of a live male neonate weighing 4 pounds 11 ounces with bilateral congenital talipes equinovarus. Conclusion: Pregnant women with ovarian cancer should be offered the opportunity to maximize their survival, including standard chemotherapeutic regimens used in nonpregnant patients.

Original language	English
Pages (from-to)	481-483
Number of pages	3
Journal	Obstetrics and gynecology
Volume	122
Issue number	2 PART2
DOIs	https://doi.org/10.1097/AOG.0b013e31828a845a
State	Published - Aug 2013

ASJC Scopus subject areas

Obstetrics and Gynecology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/AOG.0b013e31828a845a

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title = "Intraperitoneal chemotherapy in a pregnant woman with ovarian cancer",

abstract = "Background: Ovarian cancer diagnosed in pregnancy is rare. There is limited evidence to guide the choice of optimal chemotherapeutic management for treatment of disease during pregnancy. Case: A 36-year-old primigravid woman was diagnosed with stage IIB grade III serous adenocarcinoma at 12 weeks of gestation. After extensive counseling, she opted for intraperitoneal chemotherapy. She received four cycles during the course of the pregnancy, and treatment was complicated by thrombocytopenia and mild preeclampsia. Delivery occurred by cesarean at 37 weeks of gestation, resulting in the birth of a live male neonate weighing 4 pounds 11 ounces with bilateral congenital talipes equinovarus. Conclusion: Pregnant women with ovarian cancer should be offered the opportunity to maximize their survival, including standard chemotherapeutic regimens used in nonpregnant patients.",

author = "Smith, {Esther R.} and Borowsky, {Mark E.} and Jain, {Vanita Dharan}",

year = "2013",

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language = "English",

volume = "122",

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T1 - Intraperitoneal chemotherapy in a pregnant woman with ovarian cancer

AU - Smith, Esther R.

AU - Borowsky, Mark E.

AU - Jain, Vanita Dharan

PY - 2013/8

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N2 - Background: Ovarian cancer diagnosed in pregnancy is rare. There is limited evidence to guide the choice of optimal chemotherapeutic management for treatment of disease during pregnancy. Case: A 36-year-old primigravid woman was diagnosed with stage IIB grade III serous adenocarcinoma at 12 weeks of gestation. After extensive counseling, she opted for intraperitoneal chemotherapy. She received four cycles during the course of the pregnancy, and treatment was complicated by thrombocytopenia and mild preeclampsia. Delivery occurred by cesarean at 37 weeks of gestation, resulting in the birth of a live male neonate weighing 4 pounds 11 ounces with bilateral congenital talipes equinovarus. Conclusion: Pregnant women with ovarian cancer should be offered the opportunity to maximize their survival, including standard chemotherapeutic regimens used in nonpregnant patients.

AB - Background: Ovarian cancer diagnosed in pregnancy is rare. There is limited evidence to guide the choice of optimal chemotherapeutic management for treatment of disease during pregnancy. Case: A 36-year-old primigravid woman was diagnosed with stage IIB grade III serous adenocarcinoma at 12 weeks of gestation. After extensive counseling, she opted for intraperitoneal chemotherapy. She received four cycles during the course of the pregnancy, and treatment was complicated by thrombocytopenia and mild preeclampsia. Delivery occurred by cesarean at 37 weeks of gestation, resulting in the birth of a live male neonate weighing 4 pounds 11 ounces with bilateral congenital talipes equinovarus. Conclusion: Pregnant women with ovarian cancer should be offered the opportunity to maximize their survival, including standard chemotherapeutic regimens used in nonpregnant patients.

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JO - Obstetrics and gynecology

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IS - 2 PART2

ER -

Intraperitoneal chemotherapy in a pregnant woman with ovarian cancer

Abstract

ASJC Scopus subject areas

UN SDGs

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