Isolation and structural elucidation of two new glycosides from sage (Salvia officinalis L.)

Mingfu Wang; Hiroe Kikuzaki; Nanqun Zhu; Sengming Sang; Nobuji Nakatani; Chi Tang Ho

doi:https://doi.org/10.1021/jf990761p

Isolation and structural elucidation of two new glycosides from sage (Salvia officinalis L.)

Mingfu Wang, Hiroe Kikuzaki, Nanqun Zhu, Sengming Sang, Nobuji Nakatani, Chi Tang Ho

School of Environmental and Biological Sciences, Food Science

Rutgers, The State University

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

Six compounds, 1-O-(2,3,4-trihydroxy-3-methyl)butyl-6-O-feruloyl-β-D- glucopyranoside, ethyl β-D-glucopyranosyl tuberonate, p-hydroxybenzoic acid, (-)-hydroxyjasmonic acid, caffeic acid, and 4-hydroxyacetophenone 4-O-[5-O- (3,5-dimethoxy-4-hydroxybenzoy])-β-D-apiofrunosy]]-(1→2)-β-D-glu- copyranoside, were isolated from the n-butanol-soluble fraction of sage leaf extracts. Their structures were determined by spectral methods (MS, NMR, and 2D-NMR), and their antioxidant activities were measured. Among them, two new glycosides were elucidated. All of these compounds showed DPPH free radical scavenging activity at the concentration of 30 mM, and caffeic acid was the most active compound.

Original language	American English
Pages (from-to)	235-238
Number of pages	4
Journal	Journal of agricultural and food chemistry
Volume	48
Issue number	2
DOIs	https://doi.org/10.1021/jf990761p
State	Published - Feb 2000

ASJC Scopus subject areas

Chemistry(all)
Agricultural and Biological Sciences(all)

Keywords

Glycosides
Sage
Salvia officinalis L.

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https://doi.org/10.1021/jf990761p

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title = "Isolation and structural elucidation of two new glycosides from sage (Salvia officinalis L.)",

abstract = "Six compounds, 1-O-(2,3,4-trihydroxy-3-methyl)butyl-6-O-feruloyl-β-D- glucopyranoside, ethyl β-D-glucopyranosyl tuberonate, p-hydroxybenzoic acid, (-)-hydroxyjasmonic acid, caffeic acid, and 4-hydroxyacetophenone 4-O-[5-O- (3,5-dimethoxy-4-hydroxybenzoy])-β-D-apiofrunosy]]-(1→2)-β-D-glu- copyranoside, were isolated from the n-butanol-soluble fraction of sage leaf extracts. Their structures were determined by spectral methods (MS, NMR, and 2D-NMR), and their antioxidant activities were measured. Among them, two new glycosides were elucidated. All of these compounds showed DPPH free radical scavenging activity at the concentration of 30 mM, and caffeic acid was the most active compound.",

keywords = "Glycosides, Sage, Salvia officinalis L.",

author = "Mingfu Wang and Hiroe Kikuzaki and Nanqun Zhu and Sengming Sang and Nobuji Nakatani and Ho, {Chi Tang}",

year = "2000",

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doi = "https://doi.org/10.1021/jf990761p",

language = "American English",

volume = "48",

pages = "235--238",

journal = "Journal of agricultural and food chemistry",

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T1 - Isolation and structural elucidation of two new glycosides from sage (Salvia officinalis L.)

AU - Wang, Mingfu

AU - Kikuzaki, Hiroe

AU - Zhu, Nanqun

AU - Sang, Sengming

AU - Nakatani, Nobuji

AU - Ho, Chi Tang

PY - 2000/2

Y1 - 2000/2

N2 - Six compounds, 1-O-(2,3,4-trihydroxy-3-methyl)butyl-6-O-feruloyl-β-D- glucopyranoside, ethyl β-D-glucopyranosyl tuberonate, p-hydroxybenzoic acid, (-)-hydroxyjasmonic acid, caffeic acid, and 4-hydroxyacetophenone 4-O-[5-O- (3,5-dimethoxy-4-hydroxybenzoy])-β-D-apiofrunosy]]-(1→2)-β-D-glu- copyranoside, were isolated from the n-butanol-soluble fraction of sage leaf extracts. Their structures were determined by spectral methods (MS, NMR, and 2D-NMR), and their antioxidant activities were measured. Among them, two new glycosides were elucidated. All of these compounds showed DPPH free radical scavenging activity at the concentration of 30 mM, and caffeic acid was the most active compound.

AB - Six compounds, 1-O-(2,3,4-trihydroxy-3-methyl)butyl-6-O-feruloyl-β-D- glucopyranoside, ethyl β-D-glucopyranosyl tuberonate, p-hydroxybenzoic acid, (-)-hydroxyjasmonic acid, caffeic acid, and 4-hydroxyacetophenone 4-O-[5-O- (3,5-dimethoxy-4-hydroxybenzoy])-β-D-apiofrunosy]]-(1→2)-β-D-glu- copyranoside, were isolated from the n-butanol-soluble fraction of sage leaf extracts. Their structures were determined by spectral methods (MS, NMR, and 2D-NMR), and their antioxidant activities were measured. Among them, two new glycosides were elucidated. All of these compounds showed DPPH free radical scavenging activity at the concentration of 30 mM, and caffeic acid was the most active compound.

KW - Glycosides

KW - Sage

KW - Salvia officinalis L.

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DO - https://doi.org/10.1021/jf990761p

M3 - Article

C2 - 10691621

SN - 0021-8561

VL - 48

SP - 235

EP - 238

JO - Journal of agricultural and food chemistry

JF - Journal of agricultural and food chemistry

IS - 2

ER -

Isolation and structural elucidation of two new glycosides from sage (Salvia officinalis L.)

Abstract

ASJC Scopus subject areas

Keywords

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