Levodopa therapy improves motor function in HIV-infected children with extrapyramidal syndromes

M. Mintz, M. Tardieu, L. Hoyt, G. McSherry, J. Mendelson, James Oleske

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Five children with human immunodeficiency virus type-1 (HIV-1) infection, aged 4 to 13 years, manifested extrapyramidal dysfunction characterized by rigidity/stiffness, ambulation difficulties/shuffling gait, dysarthria/drooling/swallowing dysfunction, hypomimetic/inexpressive facies, and bradykinesia. Levodopa therapy caused an initial improvement in all symptoms, and the effect was sustained in most patients. Levodopa is a useful adjunctive therapy in HIV-1 infected children with extrapyramidal syndromes, by enhancing motor function and improving their quality of life.

Original languageEnglish (US)
Pages (from-to)1583-1585
Number of pages3
JournalNeurology
Volume47
Issue number6
DOIs
StatePublished - Jan 1 1996

Fingerprint

Levodopa
HIV-1
Neurologic Gait Disorders
HIV
Sialorrhea
Mobility Limitation
Dysarthria
Hypokinesia
Virus Diseases
Deglutition
Quality of Life
Therapeutics

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

Mintz, M. ; Tardieu, M. ; Hoyt, L. ; McSherry, G. ; Mendelson, J. ; Oleske, James. / Levodopa therapy improves motor function in HIV-infected children with extrapyramidal syndromes. In: Neurology. 1996 ; Vol. 47, No. 6. pp. 1583-1585.
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Levodopa therapy improves motor function in HIV-infected children with extrapyramidal syndromes. / Mintz, M.; Tardieu, M.; Hoyt, L.; McSherry, G.; Mendelson, J.; Oleske, James.

In: Neurology, Vol. 47, No. 6, 01.01.1996, p. 1583-1585.

Research output: Contribution to journalArticle

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