Lifestyle modifications in non-alcoholic fatty liver disease and non-alcoholic steatohepatitis

Konstantinos Stavropoulos, Konstantinos Imprialos, Andreas Pittaras, Charles Faselis, Puneet Narayan, Peter Kokkinos

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations

Abstract

Non-alcoholic fatty liver disease (NAFLD) is one of the most common diseases worldwide, affecting more than 30% of general population. High-fat diets, physical inactivity and obesity, all prevalent in the western societies, are strongly associated with the development and progression of NAFLD. Current drug therapies have not consistently shown substantial beneficial effects. Thus, lifestyle modification appears to be the optimal intervention in combating the disease. Accordingly, several studies have concluded that weight loss, via increase in physical activity, and dietary interventions could potential ameliorate biochemical, histological, and structural abnormalities of non-alcoholic fatty liver disease. The aim of this review is to summarize the findings of these lifestyle intervention studies and discuss the implementation of each intervention, and its effectiveness in the management of the disease in everyday clinical practice.

Original languageEnglish (US)
Pages (from-to)239-245
Number of pages7
JournalCurrent Vascular Pharmacology
Volume16
Issue number3
DOIs
StatePublished - May 1 2018
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Pharmacology

Keywords

  • Diet
  • Lifestyle modification
  • Non-alcoholic fatty liver disease
  • Non-alcoholic steatohepatitis
  • Nutrition
  • Physical activity
  • Weight loss

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