Loxapine versus chlorpromazine in paranoid schizophrenia: A double-blind study

V. B. Tuason, J. I. Escobar, M. Garvey, B. Schiele

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Newly admitted paranoid schizophrenic patients (N = 68) were treated with either loxapine or chlorpromazine for up to 4 weeks. Mean maximum dosages were 84 mg/day of loxapine and 820 mg/day of chlorpromazine. Loxapine showed efficacy superior to that of chlorpromazine, confirming earlier retrospective findings. Adverse reactions were also less troublesome with loxapine.

Original languageEnglish (US)
Pages (from-to)158-163
Number of pages6
JournalJournal of Clinical Psychiatry
Volume45
Issue number4 I
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health

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