Lymphocyte Function in Major Depressive Disorder

Steven Schleifer, Steven Keller, Arthur T. Meyerson, Marjorie J. Raskin, Kenneth L. Davis, Marvin Stein

Research output: Contribution to journalArticle

280 Citations (Scopus)

Abstract

Lymphocyte stimulation by phytohemagglutinin, concanavalin A, and pokeweed mitogen was significantly lower in a group of hospitalized depressed patients than in matched controls. The absolute number of T and B cells was lower in the depressed group, but the percentage of these cell types did not differ between the groups. These findings may be related to the altered neuroendocrine function found in patients with depressive disorders.

Original languageEnglish (US)
Pages (from-to)484-486
Number of pages3
JournalArchives of General Psychiatry
Volume41
Issue number5
DOIs
StatePublished - Jan 1 1984
Externally publishedYes

Fingerprint

Major Depressive Disorder
Lymphocytes
Pokeweed Mitogens
Phytohemagglutinins
Depressive Disorder
Lymphocyte Activation
Concanavalin A
B-Lymphocytes
T-Lymphocytes
Cells
Stimulation

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health
  • Arts and Humanities (miscellaneous)

Cite this

Schleifer, Steven ; Keller, Steven ; Meyerson, Arthur T. ; Raskin, Marjorie J. ; Davis, Kenneth L. ; Stein, Marvin. / Lymphocyte Function in Major Depressive Disorder. In: Archives of General Psychiatry. 1984 ; Vol. 41, No. 5. pp. 484-486.
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Lymphocyte Function in Major Depressive Disorder. / Schleifer, Steven; Keller, Steven; Meyerson, Arthur T.; Raskin, Marjorie J.; Davis, Kenneth L.; Stein, Marvin.

In: Archives of General Psychiatry, Vol. 41, No. 5, 01.01.1984, p. 484-486.

Research output: Contribution to journalArticle

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