Macrophage to dendritic cell transitioning induced by Toxoplasma

Jojo Reyes, George S. Yap

Research output: Contribution to journalShort surveypeer-review

Abstract

Toxoplasma gondii exploits the migratory properties of monocytes and dendritic cells to promote tissue dissemination. Recently, ten Hoeve et al. reported that the parasite effector protein GRA28 conspires with host chromatin modifiers to confer dendritic cell-like features that convert sessile macrophages into migratory cells that transport infection to distal organs.

Original languageEnglish (US)
Pages (from-to)10-11
Number of pages2
JournalTrends in Parasitology
Volume39
Issue number1
DOIs
StatePublished - Jan 2023
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Keywords

  • Toxoplasma
  • dendritic cell
  • macrophage

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