Microsomal hydroxylation of aniline in the southern armyworm, Spodoptera eridania

L. B. Brattsten, C. F. Wilkinson, M. M. Root

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17 Scopus citations


Microsomal hydroxylation of aniline in midguts of the southern armyworm, Spodoptera eridania, was found to differ in its requirements for optimal in vitro activity from those of armyworm and rat liver p-chloro N-methylaniline N-demethylase and rat liver aniline hydroxylase. Apparent Km values for armyworm aniline hydroxylase were substantially higher than those for rat liver aniline hydroxylase and the N-demethylase enzymes. The armyworm aniline hydroxylase was inhibited by several mixed-function oxidase inhibitors as well as by aldrin and nicotine and was highly inducible by pentamethylbenzene and phenobarbital.

Original languageEnglish (US)
Pages (from-to)615-620
Number of pages6
JournalInsect Biochemistry
Issue number6
StatePublished - 1976
Externally publishedYes


  • Insect aniline hydroxylation
  • Microsomal induction
  • Microsomal inhibition
  • Mixed-function oxidation


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