Multilayer Stackable Tissue Culture Platform for 3D Co-Culture

Martin Yarmush (Inventor), Anil Shrirao (Inventor), Rene Schloss (Inventor), Ileana Berrios (Inventor)

Research output: Innovation

Abstract

Invention Summary: In a native tissue inside an animal, different types of cells co-exist and communicate with one another through the surrounding microenvironment using chemical and mechanical signaling. The lack of technology to recreate such a microenvironment in in vitro models results in either under or over prediction of results using conventional two-dimensional (2D) in vitro cell culture systems. Researchers at Rutgers have developed a simple device for 3D co-culture. Unlike conventional tissue culture inserts for co-culturing cell types in two or three separate compartments, this device enables co-culturing of cells in multiple layers. The unique design allows easy assembly and handling. Spacing between layers can be customized. Market Applications: Co-culturing of cells in multiple layers Co-culturing system for drug discovering/testing Research tool for studying cell-cell communication Tissue engineering Advantages: Easy assembly and handling Flexibility of stacking multiple layers Adjustable spacing between individual layers Intellectual Property & Development Status: Patent pending. Available for licensing and/or research collaboration.
Original languageEnglish (US)
StatePublished - Mar 2019

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