Invention Summary: In a native tissue inside an animal, different types of cells co-exist and communicate with one another through the surrounding microenvironment using chemical and mechanical signaling. The lack of technology to recreate such a microenvironment in in vitro models results in either under or over prediction of results using conventional two-dimensional (2D) in vitro cell culture systems. Researchers at Rutgers have developed a simple device for 3D co-culture. Unlike conventional tissue culture inserts for co-culturing cell types in two or three separate compartments, this device enables co-culturing of cells in multiple layers. The unique design allows easy assembly and handling. Spacing between layers can be customized. Market Applications: Co-culturing of cells in multiple layers Co-culturing system for drug discovering/testing Research tool for studying cell-cell communication Tissue engineering Advantages: Easy assembly and handling Flexibility of stacking multiple layers Adjustable spacing between individual layers Intellectual Property & Development Status: Patent pending. Available for licensing and/or research collaboration.
|Original language||English (US)|
|State||Published - Mar 2019|