Extracts of purified HeLa nuclei contain DNase activities which can be separated by CM-Sephadex column chromatography into four distinct enzymes. These DNases differ in their resistance to thermal inactivation and relative activity on different substrates. Each of these DNases can increase the template-primer activity of native DNA for DNA polymerase action.
|Original language||English (US)|
|Number of pages||8|
|Journal||Biochemical and Biophysical Research Communications|
|State||Published - Aug 6 1973|
All Science Journal Classification (ASJC) codes
- Molecular Biology
- Cell Biology