Mutagenesis and imaging studies of BMP signaling mechanisms in C. elegans

Cathy Savage-Dunn, Ryan J. Gleason, Jun Liu, Richard W. Padgett

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

C. elegans has played a central role in the elucidation of the TGFβ pathway over the last two decades. This is due to the high conservation of the pathway components and the power of genetic and cell biological approaches applied toward understanding how the pathway signals. In Subheading 3, we detail approaches to study the BMP branch of the TGFβ pathway in C. elegans.

Original languageAmerican English
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages51-73
Number of pages23
DOIs
StatePublished - 2019

Publication series

NameMethods in Molecular Biology
Volume1891

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

Keywords

  • Body size
  • C. elegans
  • Coelomocytes
  • Development
  • Genetic screens
  • Imaging
  • Mesoderm
  • Mutagenesis
  • Trafficking

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