Myoclonus-dystonia, obsessive-compulsive disorder, and alcohol dependence in SGCE mutation carriers

C. W. Hess, D. Raymond, P. De Carvalho Aguiar, S. Frucht, J. Shriberg, Gary Heiman, R. Kurlan, C. Klein, S. B. Bressman, L. J. Ozelius, R. Saunders-Pullman

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

Although myoclonus and dystonia are the hallmarks of myoclonus-dystonia (M-D), psychiatric features, particularly obsessive-compulsive disorder and alcohol dependence, have been reported in three families linked to chromosome 7q21. As the epsilon sarcoglycan (SGCE) gene for M-D was subsequently identified, we evaluated the relationship between psychiatric features and SGCE mutations in these original and two additional families and confirm that OCD and alcohol dependence are associated with manifesting mutated SGCE.

Original languageEnglish (US)
Pages (from-to)522-524
Number of pages3
JournalNeurology
Volume68
Issue number7
DOIs
StatePublished - Feb 1 2007
Externally publishedYes

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Obsessive-Compulsive Disorder
Alcoholism
Mutation
Psychiatry
Sarcoglycans
Chromosomes
Genes
Myoclonic dystonia

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

Hess, C. W., Raymond, D., Aguiar, P. D. C., Frucht, S., Shriberg, J., Heiman, G., ... Saunders-Pullman, R. (2007). Myoclonus-dystonia, obsessive-compulsive disorder, and alcohol dependence in SGCE mutation carriers. Neurology, 68(7), 522-524. https://doi.org/10.1212/01.wnl.0000253188.76092.06
Hess, C. W. ; Raymond, D. ; Aguiar, P. De Carvalho ; Frucht, S. ; Shriberg, J. ; Heiman, Gary ; Kurlan, R. ; Klein, C. ; Bressman, S. B. ; Ozelius, L. J. ; Saunders-Pullman, R. / Myoclonus-dystonia, obsessive-compulsive disorder, and alcohol dependence in SGCE mutation carriers. In: Neurology. 2007 ; Vol. 68, No. 7. pp. 522-524.
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Hess, CW, Raymond, D, Aguiar, PDC, Frucht, S, Shriberg, J, Heiman, G, Kurlan, R, Klein, C, Bressman, SB, Ozelius, LJ & Saunders-Pullman, R 2007, 'Myoclonus-dystonia, obsessive-compulsive disorder, and alcohol dependence in SGCE mutation carriers', Neurology, vol. 68, no. 7, pp. 522-524. https://doi.org/10.1212/01.wnl.0000253188.76092.06

Myoclonus-dystonia, obsessive-compulsive disorder, and alcohol dependence in SGCE mutation carriers. / Hess, C. W.; Raymond, D.; Aguiar, P. De Carvalho; Frucht, S.; Shriberg, J.; Heiman, Gary; Kurlan, R.; Klein, C.; Bressman, S. B.; Ozelius, L. J.; Saunders-Pullman, R.

In: Neurology, Vol. 68, No. 7, 01.02.2007, p. 522-524.

Research output: Contribution to journalArticle

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