TY - GEN
T1 - Nir-mediated spatiotemporal control of stem cell fate using multifunctional upconversion nanoparticles
AU - Zhang, Yixiao
AU - Lee, Ki Bum
N1 - Publisher Copyright: © 2019 Omnipress - All rights reserved.
PY - 2019
Y1 - 2019
N2 - Statement of Purpose: Spatial and temporal modulation of stem cell behaviors are of great significance in the field of stem cell biology and regenerative medicine. Due to intrinsic spatial and temporal resolution, light has been vastly involved to achieve stem cell behavioral control. Current UV-Vis based approaches are highly limited, due to non-specific absorption, poor tissue penetration and photo-toxicity. On the contrary, upconversion nanoparticles (UCNPs) have gathered growing attention for vast applications due to minimal tissue absorption, high penetration depth, and minimal photo-toxicity from near-infrared (NIR) excitations. Given the significance of spatial and temporal modulations of stem cell behaviors for regenerative and tissue engineering, a biocompatible NIR-mediated stem cell differentiation manipulation method is on demand.
AB - Statement of Purpose: Spatial and temporal modulation of stem cell behaviors are of great significance in the field of stem cell biology and regenerative medicine. Due to intrinsic spatial and temporal resolution, light has been vastly involved to achieve stem cell behavioral control. Current UV-Vis based approaches are highly limited, due to non-specific absorption, poor tissue penetration and photo-toxicity. On the contrary, upconversion nanoparticles (UCNPs) have gathered growing attention for vast applications due to minimal tissue absorption, high penetration depth, and minimal photo-toxicity from near-infrared (NIR) excitations. Given the significance of spatial and temporal modulations of stem cell behaviors for regenerative and tissue engineering, a biocompatible NIR-mediated stem cell differentiation manipulation method is on demand.
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M3 - Conference contribution
T3 - Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
SP - 819
BT - Society for Biomaterials Annual Meeting and Exposition 2019
PB - Society for Biomaterials
T2 - 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
Y2 - 3 April 2019 through 6 April 2019
ER -