TY - JOUR
T1 - Partial characterization of the highly complex fucolipids from gastric mucosa
AU - Slomiany, Bronislaw L.
AU - Slomiany, Amalia
AU - Murty, Varahabhotla L.N.
N1 - Funding Information: work was supported
PY - 1979/6/13
Y1 - 1979/6/13
N2 - Six highly complex fucolipids containing 18, 20-21, 24, 28, 32, and 35-36 sugar residues, respectively, have been isolated from hog gastric mucosa. All six compounds exhibited blood-group (A+H) activities, and were different from each other with respect to the number of fucose, galactose, N-acetylglucosamine and N-acetylgalactosamine residues. Based on the results of chemical, immunological and enzymatic analyses, we suggest that the carbohydrate chains of these glycolipids are highly branched. The branches, number of which is proportional to the degree of molecular complexity, are terminated by GalNAcα1→3(Fucα1→2)Gal, Fucα1→2Gal, Galβ→GlcNAc and βGlcNAc.
AB - Six highly complex fucolipids containing 18, 20-21, 24, 28, 32, and 35-36 sugar residues, respectively, have been isolated from hog gastric mucosa. All six compounds exhibited blood-group (A+H) activities, and were different from each other with respect to the number of fucose, galactose, N-acetylglucosamine and N-acetylgalactosamine residues. Based on the results of chemical, immunological and enzymatic analyses, we suggest that the carbohydrate chains of these glycolipids are highly branched. The branches, number of which is proportional to the degree of molecular complexity, are terminated by GalNAcα1→3(Fucα1→2)Gal, Fucα1→2Gal, Galβ→GlcNAc and βGlcNAc.
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U2 - https://doi.org/10.1016/0006-291X(79)91520-1
DO - https://doi.org/10.1016/0006-291X(79)91520-1
M3 - Article
C2 - 465072
SN - 0006-291X
VL - 88
SP - 1092
EP - 1097
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 3
ER -