Plant polysaccharides utilized by gut microbiota: New players in ameliorating cognitive impairment

TY - JOUR

T1 - Plant polysaccharides utilized by gut microbiota

T2 - New players in ameliorating cognitive impairment

AU - Sun, Ying

AU - Ho, Chi Tang

AU - Zhang, Yuting

AU - Hong, Mengyu

AU - Zhang, Xin

N1 - Funding Information: This work was sponsored by Zhejiang Provincial Key Research and Development Program ( 2020C02037 ) and People-benefit Project of Ningbo ( 202002N3078 ). Publisher Copyright: © 2022 Center for Food and Biomolecules, National Taiwan University

PY - 2022

Y1 - 2022

N2 - Considerable evidence indicates the important role of gut microbiota in human health. Through the interaction with the host and diet, it secretes a myriad of metabolites to modulate biological processes essential for health. Cognitive impairment is a common feature of psychiatric and neurological disorders, which may seriously damage the quality of patients' life. Studies have found that cognitive impairment has a close relationship with gut microbiota, and plant polysaccharides intervention to maintain intestinal micro-ecological balance has a great impact on ameliorating cognitive impairment. This review introduced the interaction between gut microbiota and plant polysaccharides, and focused on signaling pathogenesis of gut microbiota in cognitive impairment. The effect of plant polysaccharides intervention on regulation of gut microbiota was also discussed, so as to provide a promising strategy for ameliorating cognitive impairment.

AB - Considerable evidence indicates the important role of gut microbiota in human health. Through the interaction with the host and diet, it secretes a myriad of metabolites to modulate biological processes essential for health. Cognitive impairment is a common feature of psychiatric and neurological disorders, which may seriously damage the quality of patients' life. Studies have found that cognitive impairment has a close relationship with gut microbiota, and plant polysaccharides intervention to maintain intestinal micro-ecological balance has a great impact on ameliorating cognitive impairment. This review introduced the interaction between gut microbiota and plant polysaccharides, and focused on signaling pathogenesis of gut microbiota in cognitive impairment. The effect of plant polysaccharides intervention on regulation of gut microbiota was also discussed, so as to provide a promising strategy for ameliorating cognitive impairment.

KW - Cognitive impairment

KW - Gut microbiota

KW - Human health

KW - Metabolites

KW - Plant polysaccharides

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U2 - https://doi.org/10.1016/j.jtcme.2022.01.003

DO - https://doi.org/10.1016/j.jtcme.2022.01.003

M3 - Review article

SN - 2225-4110

JO - Journal of Traditional and Complementary Medicine

JF - Journal of Traditional and Complementary Medicine

ER -