Potential biomarkers for predicting outcomes in CABG cardiothoracic surgeries

Isabel Preeshagul, Rajendra Gharbaran, Kyung Hwa Jeong, Ahmed Abdel-Razek, Leonard Y. Lee, Elie Elman, K. Stephen Suh

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations

Abstract

The variations in recovery time, complications, and survival among cardiac patients who have undergone coronary artery bypass graft (CABG) procedures are vast. Many formulas and theories are used to predict clinical outcome and recovery time, and current prognostic predictions are based on medical and family history, lifestyle, co-morbidities, and performance status. The identification of biomarkers that provide concrete evidence supporting clinical outcome has greatly affected the field of medicine, helping clinicians in many medicine sub-specialties to forecast clinical course. Recent studies have discovered biomarkers that may be used as predictors of cardiac patients' status post-cardiothoracic surgery, and the applications are numerous. In this review, we assess currently available cardiac biomarkers as predictors of clinical outcome for post-operative CABG patients. Data were collected from various studies in which cardiac biomarkers were measured in pre-operative and post-operative CABG patients.

Original languageEnglish (US)
Article number176
JournalJournal of Cardiothoracic Surgery
Volume8
Issue number1
DOIs
StatePublished - Jul 18 2013

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine
  • Surgery

Keywords

  • Biomarker
  • Cardiothoracic surgery
  • Clinical outcome
  • Predictive markers
  • Serum

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