## Abstract

Summary: Qvality is a C++ program for estimating two types of standard statistical confidence measures: the q-value, which is an analog of the p-value that incorporates multiple testing correction, and the posterior error probability (PEP, also known as the local false discovery rate), which corresponds to the probability that a given observation is drawn from the null distribution. In computing q-values, qvality employs a standard bootstrap procedure to estimate the prior probability of a score being from the null distribution; for PEP estimation, qvality relies upon non-parametric logistic regression. Relative to other tools for estimating statistical confidence measures, qvality is unique in its ability to estimate both types of scores directly from a null distribution, without requiring the user to calculate p-values.

Original language | English (US) |
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Pages (from-to) | 964-966 |

Number of pages | 3 |

Journal | Bioinformatics |

Volume | 25 |

Issue number | 7 |

DOIs | |

State | Published - 2009 |

## ASJC Scopus subject areas

- Computational Mathematics
- Molecular Biology
- Biochemistry
- Statistics and Probability
- Computer Science Applications
- Computational Theory and Mathematics