Racial differences in colorectal cancer mortality: The importance of stage and socioeconomic status

Stephen Marcella, Jane E. Miller

Research output: Contribution to journalArticlepeer-review

130 Scopus citations

Abstract

This investigation studies racial and socioeconomic differences in mortality from colorectal cancer, and how they vary by stage and age at diagnosis. Cox proportional hazards models were used to estimate the hazard ratio of dying from colorectal cancer, controlling for tumor characteristics and sociodemographic factors. Black adults had a greater risk of death from colorectal cancer, especially in early stages. The gender gap in mortality is wider among blacks than whites. Differences in tumor characteristics and socioeconomic factors each accounted for approximately one third of the excess risk of death among blacks. Effects of socioeconomic factors and race varied significantly by age. Higher stage-specific mortality rates and more advanced stage at diagnosis both contribute to the higher case-fatality rates from colorectal cancer among black adults, only some of which is due to socioeconomic differences. Socioeconomic and racial factors have their most significant effects in different age groups.

Original languageEnglish (US)
Pages (from-to)359-366
Number of pages8
JournalJournal of Clinical Epidemiology
Volume54
Issue number4
DOIs
StatePublished - 2001

All Science Journal Classification (ASJC) codes

  • Epidemiology

Keywords

  • Colorectal neoplasms
  • Mortality
  • Neoplasm staging
  • Racial stocks
  • Socioeconomic factors
  • Survival analysis

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