Reliability of frozen section of uterine curettings in evaluation of possible ectopic pregnancy

Debra S. Heller, Sam Hessami, Bernadette Cracchiolo, Joan H. Skurnick

Research output: Contribution to journalArticle

11 Scopus citations


Study Objective. To assess the accuracy of frozen section evaluation of uterine curettings to look for chorionic villi and rule out ectopic pregnancy before laparoscopy. Design. Retrospective review (Canadian Task Force classification III). Setting. Northeastern medical school-affiliated teaching hospital. Patients. Thirty-six women. Intervention. Dilatation and curettage, laparoscopy, and laparotomy. Measurements and Main Results. Of 36 cases, 13 showed evidence of intrauterine pregnancy, either chorionic villi or implantation site, on final permanent sections. Five false negatives were identified in which no villi were identified on frozen section, although villi or evidence of an implantation site was noted on permanent sections (sensitivity 62%, 95% Cl 0.32, 0.86). Conclusion. Frozen section evaluation of uterine curettings can produce false negative diagnoses, and this should be considered in the operative planning of women with suspected ectopic pregnancy.

Original languageEnglish (US)
Pages (from-to)519-522
Number of pages4
JournalJournal of the American Association of Gynecologic Laparoscopists
Issue number4
StatePublished - Jan 1 2000

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology

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