Representing expertise in a computer program: The serum protein diagnostic program

S. M. Weiss, C. A. Kulikowski, R. S. Galen

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


A scheme for developing expert interpretive systems and transferring them to a microprocessor environment is described. The scheme has been successfuly implemented and tested by producing a program for interpreting results from a widely used medical laboratory instrument: a scanning densitometer. Specialists in the field of serum protein electrophoresis analysis provided the knowledge needed to build an interpretive model using EXPERT, a general production rule programming system for developing consultation models. By constraining a few of the structures used in the general model, it was possible to develop procedures for automatically translating the model to a specialized application program and then to a microprocessor assembly language program. Thus, the model development can take place on a large machine, using established techniques for capturing and conveniently updating expert knowledge structures, while the final interpretive program can be targeted to a microprocessor depending on the application. The authors' experience in carrying out the complete process illustrates many of the requirements involved in taking an expert system from its early development phase to actual implementation and use in a 'real world' application.

Original languageEnglish (US)
Pages (from-to)383-387
Number of pages5
JournalJournal of Clinical Laboratory Automation
Issue number6
StatePublished - 1983

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry


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