Revisiting and revising suppressor T cells

Barry R. Bloom, Padmini Salgame, Betty Diamond

Research output: Contribution to journalReview article

211 Scopus citations

Abstract

A great deal of experimental evidence supports the phenomenon of immunological suppression. The molecular mechanisms to explain the phenomenology have, however, remained controversial. In this review, the data are reinterpreted in light of the recent advances in the understanding of T-cell subsets, the cross-regulatory properties of lymphokines and the differential presentation capacities of different antigen-presenting cell types.

Original languageEnglish (US)
Pages (from-to)131-136
Number of pages6
JournalImmunology Today
Volume13
Issue number4
DOIs
StatePublished - 1992
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Immunology

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