Abstract

Over the last several years evidence has accumulated to support the model that cell growth is regulated by hormones and growth factors. A number of these growth factors have been characterized, including epidermal growth factor (EGF), fibroblast growth factor, platelet-derived growth factor, and transforming growth factors. 1-11 The growth regulatory properties of steroid hormones, prostaglandins, and their metabolites, as well as the retinoids, have also been the subject of intensive investigation. 12-24 A common property of these compounds is that they mediate their biological actions by binding to or modulating specific high-affinity receptor sites located on target cells. The precise biochemical events leading to alterations in cell growth following activation of these receptors is varied and depends on the nature of the growth regulatory substance and on the target cell.

Original languageEnglish (US)
Title of host publicationPsoralen DNA Photobiology
PublisherCRC Press
Pages135-148
Number of pages14
Volume2
ISBN (Electronic)9781351084581
ISBN (Print)9781315897035
DOIs
StatePublished - Jan 1 2018

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Cell growth
Intercellular Signaling Peptides and Proteins
Steroid hormones
Fibroblast Growth Factors
Platelet-Derived Growth Factor
Hormones
Retinoids
Transforming Growth Factors
Growth
Metabolites
Epidermal Growth Factor
Prostaglandins
Chemical activation
Growth Substances
Steroids
psoralen receptor

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Laskin, Jeffrey ; Laskin, Debra. / Role of psoralen receptors in cell growth regulation. Psoralen DNA Photobiology. Vol. 2 CRC Press, 2018. pp. 135-148
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Role of psoralen receptors in cell growth regulation. / Laskin, Jeffrey; Laskin, Debra.

Psoralen DNA Photobiology. Vol. 2 CRC Press, 2018. p. 135-148.

Research output: Chapter in Book/Report/Conference proceedingChapter

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