Sampling and definitions of placental lesions Amsterdam placental workshop group consensus statement

T. Yee Khong, Eoghan E. Mooney, Ilana Ariel, Nathalie C.M. Balmus, Theonia K. Boyd, Marie Anne Brundler, Hayley Derricott, Margaret J. Evans, Ona M. Faye-Petersen, John E. Gillan, Alex E.P. Heazell, Debra Heller, Suzanne M. Jacques, Sarah Keating, Peter Kelehan, Ann Maes, Eileen M. McKay, Terry K. Morgan, Peter G.J. Nikkels, W. Tony ParksRaymond W. Redline, Irene Scheimberg, Mirthe H. Schoots, Neil J. Sebire, Albert Timmer, Gitta Turowski, J. Patrick Van Der Voorn, Ineke Van Lijnschoten, Sanne J. Gordijn

Research output: Contribution to journalArticle

217 Citations (Scopus)

Abstract

Context. - The value of placental examination in investigations of adverse pregnancy outcomes may be compromised by sampling and definition differences between laboratories. Objective.-To establish an agreed-upon protocol for sampling the placenta, and for diagnostic criteria for placental lesions. Recommendations would cover reporting placentas in tertiary centers as well as in community hospitals and district general hospitals, and are also relevant to the scientific research community. Data Sources.-Areas of controversy or uncertainty were explored prior to a 1-day meeting where placental and perinatal pathologists, and maternal-fetal medicine specialists discussed available evidence and subsequently reached consensus where possible. Conclusions.-The group agreed on sets of uniform sampling criteria, placental gross descriptors, pathologic terminologies, and diagnostic criteria. The terminology and microscopic descriptions for maternal vascular malperfusion, fetal vascularmalperfusion, delayed villousmaturation, patterns of ascending intrauterine infection, and villitis of unknown etiology were agreed upon. Topics requiring further discussion were highlighted. Ongoing developments in our understanding of the pathology of the placenta, scientific bases of the maternofetoplacental triad, and evolution of the clinical significance of defined lesions may necessitate further refinements of these consensus guidelines. The proposed structure will assist in international comparability of clinicopathologic and scientific studies and assist in refining the significance of lesions associated with adverse pregnancy and later health outcomes.

Original languageEnglish (US)
Pages (from-to)698-713
Number of pages16
JournalArchives of Pathology and Laboratory Medicine
Volume140
Issue number7
DOIs
StatePublished - Jul 1 2016

Fingerprint

Consensus Development Conferences
Placenta
Terminology
Mothers
District Hospitals
Information Storage and Retrieval
Community Hospital
Pregnancy Outcome
General Hospitals
Uncertainty
Blood Vessels
Medicine
Guidelines
Pathology
Pregnancy
Health
Infection
Research

All Science Journal Classification (ASJC) codes

  • Medical Laboratory Technology
  • Pathology and Forensic Medicine

Cite this

Khong, T. Y., Mooney, E. E., Ariel, I., Balmus, N. C. M., Boyd, T. K., Brundler, M. A., ... Gordijn, S. J. (2016). Sampling and definitions of placental lesions Amsterdam placental workshop group consensus statement. Archives of Pathology and Laboratory Medicine, 140(7), 698-713. https://doi.org/10.5858/arpa.2015-0225-CC
Khong, T. Yee ; Mooney, Eoghan E. ; Ariel, Ilana ; Balmus, Nathalie C.M. ; Boyd, Theonia K. ; Brundler, Marie Anne ; Derricott, Hayley ; Evans, Margaret J. ; Faye-Petersen, Ona M. ; Gillan, John E. ; Heazell, Alex E.P. ; Heller, Debra ; Jacques, Suzanne M. ; Keating, Sarah ; Kelehan, Peter ; Maes, Ann ; McKay, Eileen M. ; Morgan, Terry K. ; Nikkels, Peter G.J. ; Parks, W. Tony ; Redline, Raymond W. ; Scheimberg, Irene ; Schoots, Mirthe H. ; Sebire, Neil J. ; Timmer, Albert ; Turowski, Gitta ; Van Der Voorn, J. Patrick ; Van Lijnschoten, Ineke ; Gordijn, Sanne J. / Sampling and definitions of placental lesions Amsterdam placental workshop group consensus statement. In: Archives of Pathology and Laboratory Medicine. 2016 ; Vol. 140, No. 7. pp. 698-713.
@article{0c0cfa664c664b22903616c58b143b6a,
title = "Sampling and definitions of placental lesions Amsterdam placental workshop group consensus statement",
abstract = "Context. - The value of placental examination in investigations of adverse pregnancy outcomes may be compromised by sampling and definition differences between laboratories. Objective.-To establish an agreed-upon protocol for sampling the placenta, and for diagnostic criteria for placental lesions. Recommendations would cover reporting placentas in tertiary centers as well as in community hospitals and district general hospitals, and are also relevant to the scientific research community. Data Sources.-Areas of controversy or uncertainty were explored prior to a 1-day meeting where placental and perinatal pathologists, and maternal-fetal medicine specialists discussed available evidence and subsequently reached consensus where possible. Conclusions.-The group agreed on sets of uniform sampling criteria, placental gross descriptors, pathologic terminologies, and diagnostic criteria. The terminology and microscopic descriptions for maternal vascular malperfusion, fetal vascularmalperfusion, delayed villousmaturation, patterns of ascending intrauterine infection, and villitis of unknown etiology were agreed upon. Topics requiring further discussion were highlighted. Ongoing developments in our understanding of the pathology of the placenta, scientific bases of the maternofetoplacental triad, and evolution of the clinical significance of defined lesions may necessitate further refinements of these consensus guidelines. The proposed structure will assist in international comparability of clinicopathologic and scientific studies and assist in refining the significance of lesions associated with adverse pregnancy and later health outcomes.",
author = "Khong, {T. Yee} and Mooney, {Eoghan E.} and Ilana Ariel and Balmus, {Nathalie C.M.} and Boyd, {Theonia K.} and Brundler, {Marie Anne} and Hayley Derricott and Evans, {Margaret J.} and Faye-Petersen, {Ona M.} and Gillan, {John E.} and Heazell, {Alex E.P.} and Debra Heller and Jacques, {Suzanne M.} and Sarah Keating and Peter Kelehan and Ann Maes and McKay, {Eileen M.} and Morgan, {Terry K.} and Nikkels, {Peter G.J.} and Parks, {W. Tony} and Redline, {Raymond W.} and Irene Scheimberg and Schoots, {Mirthe H.} and Sebire, {Neil J.} and Albert Timmer and Gitta Turowski and {Van Der Voorn}, {J. Patrick} and {Van Lijnschoten}, Ineke and Gordijn, {Sanne J.}",
year = "2016",
month = "7",
day = "1",
doi = "https://doi.org/10.5858/arpa.2015-0225-CC",
language = "English (US)",
volume = "140",
pages = "698--713",
journal = "Archives of Pathology and Laboratory Medicine",
issn = "0003-9985",
publisher = "College of American Pathologists",
number = "7",

}

Khong, TY, Mooney, EE, Ariel, I, Balmus, NCM, Boyd, TK, Brundler, MA, Derricott, H, Evans, MJ, Faye-Petersen, OM, Gillan, JE, Heazell, AEP, Heller, D, Jacques, SM, Keating, S, Kelehan, P, Maes, A, McKay, EM, Morgan, TK, Nikkels, PGJ, Parks, WT, Redline, RW, Scheimberg, I, Schoots, MH, Sebire, NJ, Timmer, A, Turowski, G, Van Der Voorn, JP, Van Lijnschoten, I & Gordijn, SJ 2016, 'Sampling and definitions of placental lesions Amsterdam placental workshop group consensus statement', Archives of Pathology and Laboratory Medicine, vol. 140, no. 7, pp. 698-713. https://doi.org/10.5858/arpa.2015-0225-CC

Sampling and definitions of placental lesions Amsterdam placental workshop group consensus statement. / Khong, T. Yee; Mooney, Eoghan E.; Ariel, Ilana; Balmus, Nathalie C.M.; Boyd, Theonia K.; Brundler, Marie Anne; Derricott, Hayley; Evans, Margaret J.; Faye-Petersen, Ona M.; Gillan, John E.; Heazell, Alex E.P.; Heller, Debra; Jacques, Suzanne M.; Keating, Sarah; Kelehan, Peter; Maes, Ann; McKay, Eileen M.; Morgan, Terry K.; Nikkels, Peter G.J.; Parks, W. Tony; Redline, Raymond W.; Scheimberg, Irene; Schoots, Mirthe H.; Sebire, Neil J.; Timmer, Albert; Turowski, Gitta; Van Der Voorn, J. Patrick; Van Lijnschoten, Ineke; Gordijn, Sanne J.

In: Archives of Pathology and Laboratory Medicine, Vol. 140, No. 7, 01.07.2016, p. 698-713.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Sampling and definitions of placental lesions Amsterdam placental workshop group consensus statement

AU - Khong, T. Yee

AU - Mooney, Eoghan E.

AU - Ariel, Ilana

AU - Balmus, Nathalie C.M.

AU - Boyd, Theonia K.

AU - Brundler, Marie Anne

AU - Derricott, Hayley

AU - Evans, Margaret J.

AU - Faye-Petersen, Ona M.

AU - Gillan, John E.

AU - Heazell, Alex E.P.

AU - Heller, Debra

AU - Jacques, Suzanne M.

AU - Keating, Sarah

AU - Kelehan, Peter

AU - Maes, Ann

AU - McKay, Eileen M.

AU - Morgan, Terry K.

AU - Nikkels, Peter G.J.

AU - Parks, W. Tony

AU - Redline, Raymond W.

AU - Scheimberg, Irene

AU - Schoots, Mirthe H.

AU - Sebire, Neil J.

AU - Timmer, Albert

AU - Turowski, Gitta

AU - Van Der Voorn, J. Patrick

AU - Van Lijnschoten, Ineke

AU - Gordijn, Sanne J.

PY - 2016/7/1

Y1 - 2016/7/1

N2 - Context. - The value of placental examination in investigations of adverse pregnancy outcomes may be compromised by sampling and definition differences between laboratories. Objective.-To establish an agreed-upon protocol for sampling the placenta, and for diagnostic criteria for placental lesions. Recommendations would cover reporting placentas in tertiary centers as well as in community hospitals and district general hospitals, and are also relevant to the scientific research community. Data Sources.-Areas of controversy or uncertainty were explored prior to a 1-day meeting where placental and perinatal pathologists, and maternal-fetal medicine specialists discussed available evidence and subsequently reached consensus where possible. Conclusions.-The group agreed on sets of uniform sampling criteria, placental gross descriptors, pathologic terminologies, and diagnostic criteria. The terminology and microscopic descriptions for maternal vascular malperfusion, fetal vascularmalperfusion, delayed villousmaturation, patterns of ascending intrauterine infection, and villitis of unknown etiology were agreed upon. Topics requiring further discussion were highlighted. Ongoing developments in our understanding of the pathology of the placenta, scientific bases of the maternofetoplacental triad, and evolution of the clinical significance of defined lesions may necessitate further refinements of these consensus guidelines. The proposed structure will assist in international comparability of clinicopathologic and scientific studies and assist in refining the significance of lesions associated with adverse pregnancy and later health outcomes.

AB - Context. - The value of placental examination in investigations of adverse pregnancy outcomes may be compromised by sampling and definition differences between laboratories. Objective.-To establish an agreed-upon protocol for sampling the placenta, and for diagnostic criteria for placental lesions. Recommendations would cover reporting placentas in tertiary centers as well as in community hospitals and district general hospitals, and are also relevant to the scientific research community. Data Sources.-Areas of controversy or uncertainty were explored prior to a 1-day meeting where placental and perinatal pathologists, and maternal-fetal medicine specialists discussed available evidence and subsequently reached consensus where possible. Conclusions.-The group agreed on sets of uniform sampling criteria, placental gross descriptors, pathologic terminologies, and diagnostic criteria. The terminology and microscopic descriptions for maternal vascular malperfusion, fetal vascularmalperfusion, delayed villousmaturation, patterns of ascending intrauterine infection, and villitis of unknown etiology were agreed upon. Topics requiring further discussion were highlighted. Ongoing developments in our understanding of the pathology of the placenta, scientific bases of the maternofetoplacental triad, and evolution of the clinical significance of defined lesions may necessitate further refinements of these consensus guidelines. The proposed structure will assist in international comparability of clinicopathologic and scientific studies and assist in refining the significance of lesions associated with adverse pregnancy and later health outcomes.

UR - http://www.scopus.com/inward/record.url?scp=84965059195&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84965059195&partnerID=8YFLogxK

U2 - https://doi.org/10.5858/arpa.2015-0225-CC

DO - https://doi.org/10.5858/arpa.2015-0225-CC

M3 - Article

C2 - 27223167

VL - 140

SP - 698

EP - 713

JO - Archives of Pathology and Laboratory Medicine

JF - Archives of Pathology and Laboratory Medicine

SN - 0003-9985

IS - 7

ER -