Silver as a Bactericidal Coating for Biomedical Implants

William R. Fordham; Sean Redmond; Adam Westerland; E. G. Cortes; C. Walker; C. Gallagher; C. J. Medina; Fallon Waecther; Carl Lunk; Robert F. Ostrum; Gregory A. Caputo; Jeffrey D. Hettinger; Robert R. Krchnavek

doi:10.1016/j.surfcoat.2014.05.013

Silver as a Bactericidal Coating for Biomedical Implants

William R. Fordham
, Sean Redmond
, Adam Westerland
, E. G. Cortes
, C. Walker
, C. Gallagher
, C. J. Medina
, Fallon Waecther
, Carl Lunk
, Robert F. Ostrum
, Gregory A. Caputo
, Jeffrey D. Hettinger
, Robert R. Krchnavek

Rowan University

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Infection is a potentially serious complication of orthopedic implant surgery. While true for elective surgery, the risk of infection is significantly higher in trauma cases. Silver has been known as a broad-spectrum bactericide for centuries. In this work, we evaluate the use of silver films as bactericidal coatings on titanium-based orthopedic implants. Silver film structure and adhesion properties are presented. The silver films demonstrate bactericidal properties for bacteria that land on the surface of the film, but do little to kill bacteria in a nearby zone. This inability to create a zone of inhibition suggests that pure silver is an inadequate bactericide for orthopedic implants inserted in the medullary canal but may be useful as a coating to prevent bacterial adhesion or colonization.

Original language	English (US)
Pages (from-to)	52-57
Number of pages	6
Journal	Surface and Coatings Technology
Volume	253
DOIs	https://doi.org/10.1016/j.surfcoat.2014.05.013
State	Published - Aug 25 2014

ASJC Scopus subject areas

General Chemistry
Condensed Matter Physics
Surfaces and Interfaces
Surfaces, Coatings and Films
Materials Chemistry

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10.1016/j.surfcoat.2014.05.013

Cite this

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title = "Silver as a Bactericidal Coating for Biomedical Implants",

abstract = "Infection is a potentially serious complication of orthopedic implant surgery. While true for elective surgery, the risk of infection is significantly higher in trauma cases. Silver has been known as a broad-spectrum bactericide for centuries. In this work, we evaluate the use of silver films as bactericidal coatings on titanium-based orthopedic implants. Silver film structure and adhesion properties are presented. The silver films demonstrate bactericidal properties for bacteria that land on the surface of the film, but do little to kill bacteria in a nearby zone. This inability to create a zone of inhibition suggests that pure silver is an inadequate bactericide for orthopedic implants inserted in the medullary canal but may be useful as a coating to prevent bacterial adhesion or colonization.",

author = "Fordham, \{William R.\} and Sean Redmond and Adam Westerland and Cortes, \{E. G.\} and C. Walker and C. Gallagher and Medina, \{C. J.\} and Fallon Waecther and Carl Lunk and Ostrum, \{Robert F.\} and Caputo, \{Gregory A.\} and Hettinger, \{Jeffrey D.\} and Krchnavek, \{Robert R.\}",

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AU - Fordham, William R.

AU - Redmond, Sean

AU - Westerland, Adam

AU - Cortes, E. G.

AU - Walker, C.

AU - Gallagher, C.

AU - Medina, C. J.

AU - Waecther, Fallon

AU - Lunk, Carl

AU - Ostrum, Robert F.

AU - Caputo, Gregory A.

AU - Hettinger, Jeffrey D.

AU - Krchnavek, Robert R.

PY - 2014/8/25

Y1 - 2014/8/25

N2 - Infection is a potentially serious complication of orthopedic implant surgery. While true for elective surgery, the risk of infection is significantly higher in trauma cases. Silver has been known as a broad-spectrum bactericide for centuries. In this work, we evaluate the use of silver films as bactericidal coatings on titanium-based orthopedic implants. Silver film structure and adhesion properties are presented. The silver films demonstrate bactericidal properties for bacteria that land on the surface of the film, but do little to kill bacteria in a nearby zone. This inability to create a zone of inhibition suggests that pure silver is an inadequate bactericide for orthopedic implants inserted in the medullary canal but may be useful as a coating to prevent bacterial adhesion or colonization.

AB - Infection is a potentially serious complication of orthopedic implant surgery. While true for elective surgery, the risk of infection is significantly higher in trauma cases. Silver has been known as a broad-spectrum bactericide for centuries. In this work, we evaluate the use of silver films as bactericidal coatings on titanium-based orthopedic implants. Silver film structure and adhesion properties are presented. The silver films demonstrate bactericidal properties for bacteria that land on the surface of the film, but do little to kill bacteria in a nearby zone. This inability to create a zone of inhibition suggests that pure silver is an inadequate bactericide for orthopedic implants inserted in the medullary canal but may be useful as a coating to prevent bacterial adhesion or colonization.

UR - https://www.scopus.com/pages/publications/84904725502

UR - https://www.scopus.com/pages/publications/84904725502#tab=citedBy

U2 - 10.1016/j.surfcoat.2014.05.013

DO - 10.1016/j.surfcoat.2014.05.013

M3 - Article

SN - 0257-8972

VL - 253

SP - 52

EP - 57

JO - Surface and Coatings Technology

JF - Surface and Coatings Technology

ER -

Silver as a Bactericidal Coating for Biomedical Implants

Abstract

ASJC Scopus subject areas

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