Simulation and analysis of nerve growth cone - target encounter

Deanna M. Thompson, Helen Buettner

Research output: Contribution to conferencePaper

1 Scopus citations

Abstract

Investigation of nerve development and regeneration has revealed that the leading tip of the growing axon, the growth cone, can influence the rate and direction of growth. The filopodia especially have been implicated in a path finding role. However, due to their dynamic behavior, it has been difficult to quantitatively describe their contribution. To address this problem, we have applied a mathematical model of filopodial dynamics to examine path finding behavior. The model simulates the time required for a filopodium to contact a target at a distance, d, from the growth cone.

Original languageEnglish (US)
Pages34-35
Number of pages2
StatePublished - Jan 1 1996
EventProceedings of the IEEE 22nd Annual Northeast Bioengineering Conference - New Brunswick, NJ, USA
Duration: Mar 14 1996Mar 15 1996

Other

OtherProceedings of the IEEE 22nd Annual Northeast Bioengineering Conference
CityNew Brunswick, NJ, USA
Period3/14/963/15/96

All Science Journal Classification (ASJC) codes

  • Bioengineering

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    Thompson, D. M., & Buettner, H. (1996). Simulation and analysis of nerve growth cone - target encounter. 34-35. Paper presented at Proceedings of the IEEE 22nd Annual Northeast Bioengineering Conference, New Brunswick, NJ, USA, .