Sputum cytology in pulmonary sarcoidosis

S. C. Aisner, P. K. Gupta, J. K. Frost

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


The results of sputum cytology in patients with pulmonary sarcoidosis were investigated. All cases of pulmonary sarcoidosis with roentgenographic evidence of pulmonary interstitial fibrosis and scarring revealed diagnostically significant cytologic features in their pulmonary material. These include multinucleated epithelioid giant cells, epithelioid cells and lymphoid mononuclear cells in an otherwise noninflammatory, clean specimen. The characteristic cells occur in streaks, either singly or as a syncytium. They are dark, cyanophilic with little phagocytic activity. Schaumann and asteroid bodies may be present. Cytologic examination of induced sputum specimens in asymptomatic patients of suspected pulmonary sarcoidosis with interstitial involvement can help in the diagnosis and management of these cases.

Original languageEnglish (US)
Pages (from-to)394-398
Number of pages5
JournalActa Cytologica
Issue number3
StatePublished - 1977
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology


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