SSU71, encoding the largest subunit of TFIIF, is located on the right arm of chromosome VII in Saccharomyces cerevisiae

Zu‐Wen ‐W Sun, Michael Hampsey

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

SSU71 (TFG1) is an essential nuclear gene encoding the largest subunit of the yeast general transcription factor TFIIF. The SSU71 gene was physically mapped to the right arm of chromosome VII, physically linked to QCR9, by hybridization of the cloned gene to CHEF and lambda clone grid blots. This assignment was confirmed by genetic mapping. A search of the nucleotide sequence databases revealed that SSU71 is immediately adjacent to the TYS1 gene, which encodes tRNATyr synthetase. TYS1 was reported previously to lie on chromosome XV based on sequence overlap with the adjacent UBR1 gene. The mapping data reported here established that TYS1 and UBR1 do not lie on chromosome XV; rather the SSU71‐TYS1‐UBR1 gene cluster lies on the right arm of chromosome VII, physically linked to QCR9 and genetically linked to ade3 and ser2.

Original languageEnglish (US)
Pages (from-to)789-791
Number of pages3
JournalYeast
Volume11
Issue number8
DOIs
StatePublished - Jun 30 1995
Externally publishedYes

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Genetics

Keywords

  • QCR9
  • SSU71
  • Saccharomyces cerevisiae
  • TFG1
  • TYS1
  • UBR1
  • chromosome VII

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