Sternotomy infections with Mycoplasma hominis

D. O. Steffenson, J. S. Dummer, M. S. Granick, A. W. Pasculle, B. P. Griffith, G. H. Cassell

Research output: Contribution to journalArticlepeer-review

50 Scopus citations


Mycoplasma hominis caused sternal wound infections with mediastinitis in three patients. One infection occurred in a nonimmunocompromised man after coronary artery bypass grafting. The wound did not heal after repeated debridement, closed irrigation of the mediastinum with povidone-iodine solution, and antimycoplasmal chemotherapy; muscle flap grafting was eventually required. Two infections occurred in recipients of heart-lung transplants after the isolation of mycoplasma from bronchial secretions. Although no Mycoplasma species were isolated after specific antimycoplasmal therapy was begun, the wounds still did not heal. Both patients died of other complications. Infection of wounds after sternotomy is another of an increasing number of infections caused by M. hominis in the normal and immunocompromised host. Familiarity with the morphologic characteristics of M. hominis on bacteriologic culture media may increase the recognition of this pathogen in atypical clinical settings.

Original languageEnglish (US)
Pages (from-to)204-208
Number of pages5
JournalAnnals of internal medicine
Issue number2
StatePublished - 1987
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Internal Medicine


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