Keyphrases
Structure-activity Relationship
100%
Heterocycles
100%
Topoisomerase I Poison
100%
Methoxyphenyl
100%
Benzimidazole
100%
Topoisomerase
80%
Nitro
40%
1H-benzimidazole
40%
Substituted Benzimidazoles
40%
Hydrogen Bonds (H-bonds)
20%
Complex Formation
20%
DNA Complex
20%
High Activity
20%
Cytotoxicity
20%
Topoisomerase Inhibitors
20%
DNA Binding Affinity
20%
Relative Activity
20%
Cleavable Complex
20%
Camptothecin
20%
Cross-resistance
20%
Indole
20%
Positional Isomers
20%
Formyl
20%
Nitro Group
20%
Bibenzimidazole
20%
Structural Specificity
20%
Benzothiazole
20%
Nitro Derivatives
20%
Heterocyclic Analogs
20%
Benzoxazole
20%
Chemistry
Deoxyribonucleic Acid
100%
Heterocyclic Compound
100%
Structure-Activity Relationship
100%
Benzimidazole
100%
1H-Benzimidazole
66%
Hydrogen Bonding
33%
Structure
33%
Kd
33%
Indole
33%
Benzoxazoles
33%
Nitro Group
33%
Camptothecin
33%
Benzothiazole
33%
Bibenzimidazole
33%
EC 5.99.1.2 (DNA Topoisomerase) Inhibitor
33%
Pharmacology, Toxicology and Pharmaceutical Science
Structure Activity Relationship
100%
DNA Topoisomerase
100%
Benzimidazole Derivative
100%
Cytotoxicity
14%
Hydrogen Bond
14%
Camptothecin
14%
Cross-Resistance
14%
Indole
14%
Benzoxazole Derivative
14%
DNA Topoisomerase Inhibitor
14%
Benzimidazole
14%
Nitro Derivative
14%
Benzothiazole
14%