Supercooling enables long-term transplantation survival following 4 days of liver preservation

Tim A. Berendsen, Bote G. Bruinsma, Catheleyne F. Puts, Nima Saeidi, O. Berk Usta, Basak E. Uygun, Maria Louisa Izamis, Mehmet Toner, Martin L. Yarmush, Korkut Uygun

Research output: Contribution to journalArticlepeer-review

88 Scopus citations

Abstract

The realization of long-term human organ preservation will have groundbreaking effects on the current practice of transplantation. Herein we present a new technique based on subzero nonfreezing preservation and extracorporeal machine perfusion that allows transplantation of rat livers preserved for up to four days, thereby tripling the viable preservation duration.

Original languageEnglish (US)
Pages (from-to)790-793
Number of pages4
JournalNature Medicine
Volume20
Issue number7
DOIs
StatePublished - Jul 2014

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

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