Synteny between the loci for a novel FACIT-like collagen locus (D6S228E) and α1(IX) collagen (COL9A1) on 6q12-q14 in humans

Hidekatsu Yoshioka, Hui Zhang, Francesco Ramirez, Marie Genevieve Mattei, Mahnaz Moradi-Ameli, Michel van der Rest, Marion K. Gordon

Research output: Contribution to journalArticlepeer-review

43 Scopus citations

Abstract

A 1.8-kb cDNA encoding portion of a novel collagenous chain was isolated from a human rhabdomyosarcoma cell line by cross-hybridization using a chicken type V collagen probe. Sequence analysis suggests that this chain belongs to the recently discovered group of collagens, termed the FACIT class of macromolecules. This cDNA was used to locate the corresponding gene (D6S228E) to chromosome 6, notably at position 6q12-q14. Interestingly, within this region of human chromosome 6 resides the α1(IX) collagen gene (COL9A1), a member of the FACIT group.

Original languageEnglish (US)
Pages (from-to)884-886
Number of pages3
JournalGenomics
Volume13
Issue number3
DOIs
StatePublished - Jul 1992
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Genetics

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