Synthesis and evaluation of functionalized aminobenzoboroxoles as potential anti-cancer agents

Pathi Suman, Bhawankumar P. Patel, Agasthya V. Kasibotla, Lucas N. Solano, Subash C. Jonnalagadda

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Several aminobenzoboroxole derivatives have been prepared starting from o-boronobenzaldehyde employing reductive amination protocol. The corresponding aminobenzoboroxole derivatives have been further functionalized as N-nitrosoaminobenzoboroxoles as well as N-benzoboroxolylureas. These derivatives have been evaluated for their anti-cancer activity on human pancreatic cancer MIAPaCa-2 and human breast cancer MDA-MB-231 cell lines. 2015 Elsevier Ltd. All rights reserved.

Original languageEnglish (US)
Pages (from-to)125-131
Number of pages7
JournalJournal of Organometallic Chemistry
Volume798
DOIs
StatePublished - Dec 1 2015

All Science Journal Classification (ASJC) codes

  • Materials Chemistry
  • Biochemistry
  • Inorganic Chemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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