The Dynamic Identity of Intestinal Cancer Stem Cells

Piero Dalerba

doi:10.1016/j.stem.2017.05.018

The Dynamic Identity of Intestinal Cancer Stem Cells

Piero Dalerba

Center for Discovery and Innovation

Hackensack Meridian School of Medicine

Research output: Contribution to journal › Short survey › peer-review

Abstract

Elimination of self-renewing cancer stem cells (CSCs) is necessary to permanently eradicate malignant tissues. In a recent article in Nature, de Sousa e Melo et al. (2017) reveal that intestinal tumors can contain dynamic pools of functionally distinct CSC populations, which seem to interconvert depending on the host tissue microenvironment. Elimination of self-renewing cancer stem cells (CSCs) is necessary to permanently eradicate malignant tissues. In a recent article in Nature, de Sousa e Melo et al. (2017) reveal that intestinal tumors can contain dynamic pools of functionally distinct CSC populations, which seem to interconvert depending on the host tissue microenvironment.

Original language	English
Pages (from-to)	743-745
Number of pages	3
Journal	Cell stem cell
Volume	20
Issue number	6
DOIs	https://doi.org/10.1016/j.stem.2017.05.018
State	Published - Jun 1 2017

ASJC Scopus subject areas

Molecular Medicine
Genetics
Cell Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.stem.2017.05.018

Cite this

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title = "The Dynamic Identity of Intestinal Cancer Stem Cells",

abstract = "Elimination of self-renewing cancer stem cells (CSCs) is necessary to permanently eradicate malignant tissues. In a recent article in Nature, de Sousa e Melo et al. (2017) reveal that intestinal tumors can contain dynamic pools of functionally distinct CSC populations, which seem to interconvert depending on the host tissue microenvironment. Elimination of self-renewing cancer stem cells (CSCs) is necessary to permanently eradicate malignant tissues. In a recent article in Nature, de Sousa e Melo et al. (2017) reveal that intestinal tumors can contain dynamic pools of functionally distinct CSC populations, which seem to interconvert depending on the host tissue microenvironment.",

author = "Piero Dalerba",

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AB - Elimination of self-renewing cancer stem cells (CSCs) is necessary to permanently eradicate malignant tissues. In a recent article in Nature, de Sousa e Melo et al. (2017) reveal that intestinal tumors can contain dynamic pools of functionally distinct CSC populations, which seem to interconvert depending on the host tissue microenvironment. Elimination of self-renewing cancer stem cells (CSCs) is necessary to permanently eradicate malignant tissues. In a recent article in Nature, de Sousa e Melo et al. (2017) reveal that intestinal tumors can contain dynamic pools of functionally distinct CSC populations, which seem to interconvert depending on the host tissue microenvironment.

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DO - 10.1016/j.stem.2017.05.018

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JO - Cell stem cell

JF - Cell stem cell

IS - 6

ER -

The Dynamic Identity of Intestinal Cancer Stem Cells

Abstract

ASJC Scopus subject areas

UN SDGs

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