The neutral theory in light of natural selection

Matthew W. Hahn

Research output: Contribution to journalReview articlepeer-review

46 Scopus citations

Abstract

In this perspective, we evaluate the explanatory power of the neutral theory of molecular evolution, 50 years after its introduction by Kimura. We argue that the neutral theory was supported by unreliable theoretical and empirical evidence from the beginning, and that in light of modern, genome-scale data, we can firmly reject its universality. The ubiquity of adaptive variation both within and between species means that a more comprehensive theory of molecular evolution must be sought.

Original languageEnglish (US)
Pages (from-to)1366-1371
Number of pages6
JournalMolecular Biology and Evolution
Volume35
Issue number6
DOIs
StatePublished - Jun 2018

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics

Keywords

  • Natural selection
  • Neutral theory
  • Population genetics

Fingerprint

Dive into the research topics of 'The neutral theory in light of natural selection'. Together they form a unique fingerprint.

Cite this